Over 50% of egg chambers from 2 day old spno^A42/spno^rev6 females contain more than 15 nurse cells, some contain more than 30 of these cells. The nurse cells are variable in size. Some chambers appear necrotic, with condensed and pycnotic chromosomes, the frequency of necrotic chambers increases with age. Stalk cells between successive chambers are not always apparent. Microtubule distribution within the egg chamber is abnormal. spno^A42/spno^rev6 males have reduced fertility. The testes of spno^A42/spno^rev6 males contain large numbers of primary spermatocytes which show no distinct organisation into cysts, and the testis tip is often expanded to accommodate these cells. Groups of 16 cells undergoing meiosis are not seen, suggesting that there is a loss of synchronous entry into meiosis. Smaller numbers of spermatids than normal are seen.

Many variably sized nuclei scattered in blastoderm embryo cytoplasm. 90% of eggs from spno^A42/spno^rev6 females fail to hatch. Phenotype of non-hatchers is milder than for spno^2-210/Df(3R)sbd105, with embryos reaching germ band shortening before development ceases.