FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Syt1N19
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General Information
Symbol
Dmel\Syt1N19
Species
D. melanogaster
Name
FlyBase ID
FBal0032849
Feature type
allele
Associated gene
Dmel\Syt1
Associated Insertion(s)
P{5'lacW}Syt1N19
Carried in Construct
Key Links
Allele class

amorphic allele - genetic evidence

Mutagen
Nature of the Allele
Allele class

amorphic allele - genetic evidence

(Littleton et al., 1993)
Mutagen
Delta2-3 transposase
(Littleton and Bellen, 1994, Littleton et al., 1993)
Progenitor genotype
Syt1T77
(Littleton and Bellen, 1994, Littleton et al., 1993)
Associated Insertion(s)
P{5'lacW}Syt1N19
Caused by aberration
Df(2L)N19
Cytology
Description

Imprecise excision of P-element from sytT77.

(Littleton and Bellen, 1994)

Deletion removing genomic DNA between P elements in sytT77 and P{lacW}B8-2-30, which includes the entire open reading frame of syt.

(Littleton et al., 1993)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Embryos show severe reduction in coordinated muscle contraction when compared with wild type, and an increase in uncoordinated twitching.

      (Littleton et al., 1993)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      Comments
      Comments

      The syt alleles form a series: going from most severe to least severe, sytN19 = sytN6 >= sytT7 = sytT41 > sytT77 = syt66.4 > sytT11.

      (Littleton et al., 1993)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (4)
      Reported As
      Symbol Synonym
      Df(2L)N19
      (Littleton et al., 1993)
      Syt1N19
      SytN19
      (Bellen, 2020.5.15)
      sytN19
      Name Synonyms
      Secondary FlyBase IDs
        References (3)