FlyBase Allele Report: Dmel\unk[OR20]

General Information

Symbol

Dmel\unk^OR20

Species

D. melanogaster

Name

FlyBase ID

FBal0032978

Feature type

allele

Associated gene

Dmel\unk

Associated Insertion(s)

P{wA^R}unk^OR20

Carried in Construct

Key Links

Genomic Maps

JBrowse

Allele class

Mutagen

P-element activity

Nature of the Allele

Allele class

Mutagen

P-element activity

(Mohler et al., 1992)

Progenitor genotype

Associated Insertion(s)

P{wA^R}unk^OR20

Cytology

Description

P{wA^R} insertion within unk at about position -36kb on the hh cnc map within the second intron of unk. Original insertion position at -31kb (FBrf0054619) is incorrect.

(Mohler et al., 1992)

P{wA^R} insertion at position -31kb, within unk, of the hh cnc map.

(Mohler et al., 1991)

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

transposable_element_insertion_site

3R:23,156,776..23,157,500 [-]

(Mohler et al., 1995, Mohler and Vasilakis, 1992, Mohler et al., 1992, Mohler et al., 1991)

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

lethal | recessive

(Mohler et al., 1992, Mohler et al., 1991)

Phenotype Manifest In

embryonic head

(Mohler et al., 1991)

ommatidium

(Mohler et al., 1992)

scutellar bristle

(Mohler et al., 1992)

wing

(Mohler et al., 1992)

Detailed Description

Statement

Reference

Heterozygotes with unk^R16 exhibit the 'unkempt' cuticular defects: roughened eyes, splayed wings and crossed scutellar bristles.

(Mohler et al., 1992)

Failure head involution.

(Mohler et al., 1991)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

Comments

Originally described in Levis et al., Science 229:558--561 .

(Mohler and Vasilakis, 1992)

Loss of the P{wA^R} element demonstrates the insertion is the cause of the lethal phenotype.

(Mohler et al., 1992)

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

unk¹

unk^OR20

Name Synonyms

Secondary FlyBase IDs

FBal0032977

References (4)

Report Sections

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