FlyBase Allele Report: Dmel\unk[R14]

General Information

Symbol

Dmel\unk^R14

Species

D. melanogaster

Name

FlyBase ID

FBal0032980

Feature type

allele

Associated gene

Dmel\unk

Associated Insertion(s)

P{?'wA^R}unk^R14

Carried in Construct

Key Links

Genomic Maps

JBrowse

Allele class

Mutagen

PM hybrid dysgenesis

Nature of the Allele

Allele class

Mutagen

PM hybrid dysgenesis

(Mohler et al., 1992)

Progenitor genotype

unk^OR20

(Mohler et al., 1992)

Associated Insertion(s)

P{?'wA^R}unk^R14

Cytology

Description

Imprecise excision of the P{wA^R} insertion causing deletion of flanking genomic DNA and part of insertion.

(Mohler et al., 1992)

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

sequence_alteration

3R:23,156,298..23,157,500 [-]

Comment:

position of lesion based on the site of P{wA^R}unk^OR20 insertion plus the adjoining XhoI-PstI site, as shown in Figure 4 of FBrf0056221

(Mohler et al., 1992)

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

lethal - all die before end of pupal stage | recessive

(Mohler et al., 1992)

some die during pupal stage | recessive

(Mohler et al., 1992)

Phenotype Manifest In

Detailed Description

Statement

Reference

Nervous system of homozygous embryos at stage 16 and 17 shows no gross abnormalities. Mutant larvae reach the third larval instar approximately one day later that wild type and pupariate three days after wild type. Most developmentally delayed larvae possess one or more amorphous melanotic tumours at various locations within the abdomen. Development stops during the mid-pupal phase.

(Mohler et al., 1992)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

Comments

Strong allele of unk.

(Mohler et al., 1992)

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

unk^R14

Name Synonyms

Secondary FlyBase IDs

References (1)

Report Sections

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