hyperplasia
lethal - all die before end of pupal stage
some die during pupal stage
larval brain
mesothoracic leg disc
metathoracic leg disc
prothoracic leg disc
Brain is asymmetric with elongated or cuboidal hemispheres. Leg discs are especially large, hyperplastic outgrowths.
P-element excision demonstrates the insertion to be the cause of lethality.
P-element excision demonstrates the insertion to be the cause of lethality.