FB2026_02 , released June 18, 2026
Allele: Dmel\mysrDEA
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General Information
Symbol
Dmel\mysrDEA
Species
D. melanogaster
Name
FlyBase ID
FBal0035244
Feature type
allele
Associated gene
Dmel\mys
Associated Insertion(s)
Carried in Construct
P{mysrDEA}
Key Links
Transgenic product class
missense_variant
(Grinblat et al., 1994)
Mutagen
Nature of the Allele
Transgenic product class
missense_variant
(Grinblat et al., 1994)
Mutagen
in vitro construct
(Grinblat et al., 1994)
Progenitor genotype
mystZa
(Grinblat et al., 1994)
Carried in construct
P{mysrDEA}
Cytology
Description

A D to A and an E to A mutation, in the α helix in the cytoplasmic domain.

(Grinblat et al., 1994)
Allele components
Component
Use(s)
Regulatory region(s)
mys
Encoded product / tool
mys
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      mysrDEA rescues mys11

      (Grinblat et al., 1994)
      Partially rescues

      mysrDEA partially rescues mys11

      (Li et al., 1998)

      mysrDEA partially rescues mys8

      (Grinblat et al., 1994)
      Comments

      Germband separation, midgut constrictions, midgut migration and elongation and holes in the embryonic cuticle of mys11 embryos are rescued.

      (Li et al., 1998)

      Alleviates dorsal hole defect of mys11. Embryonic muscle attachment defect is also rescued, at least to the extent that the embryos can move. Rescues eye disc defect of mys11. Rescues the wing disc blister defect of mys11. Partially rescues the wing posture defect of mys8.

      (Grinblat et al., 1994)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      mysrDEA
      Name Synonyms
      Secondary FlyBase IDs
        References (2)