FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\twiHH07
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General Information
Symbol
Dmel\twiHH07
Species
D. melanogaster
Name
FlyBase ID
FBal0035884
Feature type
allele
Associated gene
Dmel\twi
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
    Nature of the Allele
    Allele class
    Mutagen
    Progenitor genotype
    Cytology
    Description
    Mutations Mapped to the Genome
    Curation Data
    Type
    Location
    Additional Notes
    References
    Variant Molecular Consequences
    Associated Sequence Data
    DDBJ / EMBL / GenBank
    DNA sequence
    Protein sequence
     
    UniProtKB/Swiss-Prot
      UniProtKB/TrEMBL
        Expression Data
        Reporter Expression
        Additional Information
        Statement
        Reference
         
        Marker for
        Reflects expression of
        Reporter construct used in assay
        Human Disease Associations
        Disease Ontology (DO) Annotations
        Models Based on Experimental Evidence ( 0 )
        Disease
        Evidence
        References
        Modifiers Based on Experimental Evidence ( 0 )
        Disease
        Interaction
        References
        Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
         
        Disease-implicated variant(s)
         
        Phenotypic Data
        Phenotypic Class
        Phenotype Manifest In
        Detailed Description
        Statement
        Reference

        In twiHH07, sna19 double mutants the endoderm becomes internalized during gastrulation, but does not form an epithelium.

        (Tepass and Hartenstein, 1994)
        External Data
        Interactions
        Show genetic interaction network for Enhancers & Suppressors
        Phenotypic Class
        Phenotype Manifest In
        NOT Enhancer of
        Statement
        Reference

        twiHH07 is a non-enhancer of adult Malpighian tubule Type II cell phenotype of sna19

        (Denholm et al., 2003)
        NOT Suppressor of
        Statement
        Reference

        twiHH07 is a non-suppressor of adult Malpighian tubule Type II cell phenotype of sna19

        (Denholm et al., 2003)
        Other
        Additional Comments
        Genetic Interactions
        Statement
        Reference

        In sna19, twiHH07 double mutants, despite the loss of the caudal visceral mesoderm (CVM) stellate cells still remain though their numbers are strongly reduced.

        (Denholm et al., 2003)

        twiHH07, sna19 double mutants lack head mesoderm, and hemocytes and macrophages.

        (Tepass et al., 1994)
        Xenogenetic Interactions
        Statement
        Reference
        Complementation and Rescue Data
        Comments
        Images (0)
        Mutant
        Wild-type
        Stocks (0)
        Notes on Origin
        Discoverer

        Nusslein-Volhard, Wieschaus and Kluding.

        (Tepass and Hartenstein, 1994)
        Comments
        Comments

        Strong twi allele.

        (Tepass and Hartenstein, 1994)
        External Crossreferences and Linkouts ( 0 )
        Synonyms and Secondary IDs (1)
        Reported As
        Symbol Synonym
        twiHH07
        Name Synonyms
        Secondary FlyBase IDs
          References (3)