FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Ecol\lacZHsp70Bb.70ZT
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General Information
Symbol
Ecol\lacZHsp70Bb.70ZT
Species
E. coli
Name
FlyBase ID
FBal0038876
Feature type
allele
Associated gene
Ecol\lacZ
Associated Insertion(s)
Carried in Construct
P{cp70ZT}
Also Known As
hsp70-lacZ
Transgenic product class
Mutagen
Nature of the Allele
Transgenic product class
Mutagen
in vitro construct
(Lu et al., 1995, Xiao and Lis, 1989, Simon et al., 1985)
Progenitor genotype
Ecol\lacZHsp70Bb.-194
(Simon et al., 1985)
Carried in construct
P{cp70ZT}
Cytology
Description

Hsp70Bb promoter sequences from -194 to +260 fused in frame to lacZ coding region.

(Lu et al., 1995)

An Hsp70Bb promoter fragment (extends to -194 relative to the transcription start site) is fused upstream of lacZ. 148bp of 3' Hsp70 sequence, including a polyadenylation signal, is also present downstream of the lacZ coding sequence.

(Simon et al., 1985)
Allele components
Component
Use(s)
Encoded product / tool
lacZ
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference

      200-fold increase in transcription level observed upon heat-shock; assayed by mRNA levels on northern blots and by quantitation of β-galactosidase activity. Used as wild-type standard.

      (Simon and Lis, 1987)
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      Ecol\lacZHsp70Bb.70ZT
      lacZHsp70Bb.70ZT
      lacZhs.T1
      Name Synonyms
      Secondary FlyBase IDs
      • FBal0041607
      References (10)