FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\aosp1e20
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General Information
Symbol
Dmel\aosp1e20
Species
D. melanogaster
Name
FlyBase ID
FBal0039373
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Nature of the Allele
Allele class
Progenitor genotype
Cytology
Description

Generated by imprecise excision of P-element in P{PZ}argosp1.

Generated by P-element excision.

Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DNA sequence
Protein sequence
 
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Semilethal. Rough eye phenotype. Supernumerary photoreceptor cells and abnormal spacing pattern of ommatidia. Wings have small deltas and extra veins.

Semilethal. Rough eye phenotype. Pattern of wing vein network is abnormal. Extra rudimentry bristles on the abdominal sternite in ectopic positions.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Rescued by
Comments

The low viability of argosp1e20 homozygotes is rescued by two copies of argoshs.PSb in the absence of heat shock. Expression of argoshs.PSb using heat shock almost completely rescues the external morphology of the eyes of argosp1e20 homozygotes. When argoshs.PSb is expressed using heat pulses after the wandering larval stage in argosp1e20 homozygotes, only the anterior half of the eye shows normal morphology. Expression of argoshs.PSb using heat shock also rescues the ommatidial pattern of argosp1e20 homozygotes. Expression of argoshs.PSb using a single heat pulse for 1 hour at 38oC during the third larval instar in argosp1e20 homozygotes generates a region of the eye in which most ommatidia contain the normal number of 4 cone cells, although some ommatidia in this region contain fewer cone cells than normal. As the distance from the rescued region increases, the number of extra cone cells in the ommatidia gradually increases. The abnormal wing vein and maxillary palp morphology of argosp1e20 homozygotes is rescued by expression of two copies of argoshs.PSb using heat shock.

Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (6)
Reported As
Symbol Synonym
aosp1e20
argosp1e20
gilp1e20
styP1e20
Name Synonyms
Secondary FlyBase IDs
    References (2)