FlyBase Allele Report: Dmel\aos[p1]

General Information

Symbol

Dmel\aos^p1

Species

D. melanogaster

Name

FlyBase ID

FBal0039372

Feature type

allele

Associated gene

Dmel\aos

Associated Insertion(s)

P{PZ}aos^p1

Carried in Construct

Also Known As

argos^sty1

Key Links

Allele class

Mutagen

P-element activity

Nature of the Allele

Allele class

Mutagen

P-element activity

(Okano et al., 1992)

Progenitor genotype

Associated Insertion(s)

P{PZ}aos^p1

Cytology

Description

P-element insertion within the 5' regulatory region.

(Okano et al., 1992)

Allele components

Component

Use(s)

Inserted element

P{PZ}

enhancer trap

Encoded product / tool

lacZ

reporter enzyme

Tagged with

Tag:NLS(P)

nuclear protein localization tag

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

visible (with aos^Δ7)

(Zartman et al., 2009)

Phenotype Manifest In

dorsal appendage | maternal effect (with aos²⁵⁷)

(Zartman et al., 2009)

eye (with aos^Δ7)

(Zartman et al., 2009)

eye photoreceptor cell

(Okano et al., 1992)

interommatidial bristle

(Okano et al., 1992)

photoreceptor cell R8

(Spencer et al., 1998)

rhabdomere

(Okano et al., 1992)

Detailed Description

Statement

Reference

argos^Δ7/argos^p1 flies have blisters in the eye.

Only 3% of eggs derived from argos²⁵⁷/argos^p1 females have defects in dorsal appendage morphology.

(Zartman et al., 2009)

Ectopic R8 cells form in positions between the normal ommatidial rows in homozygous imaginal discs.

(Spencer et al., 1998)

Severe rough eye phenotype.

(Okano et al., 1992)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhancer of

Statement

Reference

argos[+]/aos^p1 is an enhancer of visible phenotype of Scer\GAL4^en-e16E, tum^ΔE1E.UAS

(Sotillos and Campuzano, 2000)

Suppressor of

Statement

Reference

argos[+]/aos^p1 is a suppressor of visible phenotype of rg^γ10

(Shamloula et al., 2002)

Phenotype Manifest In

Enhancer of

Statement

Reference

argos[+]/aos^p1 is an enhancer of sensillum campaniformium & wing vein | supernumerary phenotype of Scer\GAL4^en-e16E, tum^ΔE1E.UAS

(Sotillos and Campuzano, 2000)

Suppressor of

Statement

Reference

argos[+]/aos^p1 is a suppressor of eye phenotype of rg^γ10

(Shamloula et al., 2002)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Fails to complement

aos^Δ7

(Zartman et al., 2009)

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

Comments

Precise excision of the P-element results in reversion of the mutant phenotype to wild type.

(Okano et al., 1992)

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (10)

Reported As

Symbol Synonym

aos^p1

arg^sty1

(Sawamoto et al., 1994)

arg^sty

(Sotillos and Campuzano, 2000)

argos^P1

(Zartman et al., 2009)

argos^p1

argos^sty1

(Shamloula et al., 2002, Sawamoto et al., 1996)

argos^styP1

(Spencer et al., 1998)

gil^p1

sty^P1

sty^p1

(Okano et al., 1992)

Name Synonyms

Secondary FlyBase IDs

References (7)

Report Sections

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