FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\klarmarb-BX5
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General Information
Symbol
Dmel\klarmarb-BX5
Species
D. melanogaster
Name
FlyBase ID
FBal0039640
Feature type
allele
Associated gene
Dmel\klar
Associated Insertion(s)
Carried in Construct
Also Known As
klarmBX5
Key Links
Genomic Maps

Allele class

loss of function allele

Mutagen
Nature of the Allele
Allele class

loss of function allele

(Fischer-Vize and Mosley, 1994)
Mutagen
X ray
(Fischer-Vize and Mosley, 1994)
Progenitor genotype
Cytology

Polytene chromosomes normal.

(Fischer-Vize and Mosley, 1994)
Description

Deletion of 10bp, starting at position 238, resulting in a frameshift in the open reading frame after amino acid 79.

(Fischer et al., 2004)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
deletion
3L:508,265..508,274 [-]
Comment:

Reported as a deletion of 10bp (AATAAGGCCG) resulting in a frameshift after amino acid 79. The sequence at this location in the reference sequence is AATAGGGCCG. Position of mutation on reference sequence inferred by FlyBase curator.

(Fischer et al., 2004)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Rough eye phenotype. Notal bristles point in unusual directions.

      (Fischer-Vize and Mosley, 1994)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      NOT Enhancer of
      Statement
      Reference

      klarmarb-BX5 is a non-enhancer of photoreceptor cell | precursor & nucleus phenotype of Scer\GAL4unspecified, msnDN.UAS

      (Houalla et al., 2005)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      0% of animals expressing msnDN.Scer\UAS in the developing eye, combined with klarmarb-BX5/+ exhibit a R-cell nuclear migration phenotype.

      (Houalla et al., 2005)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (4)
      Reported As
      Symbol Synonym
      klarmBX5
      (Houalla et al., 2005, Fischer et al., 2004)
      klarmarb-BX5
      klsmarb-BX5
      marbBX5
      Name Synonyms
      Secondary FlyBase IDs
        References (3)