FB2026_02 , released June 18, 2026
Allele: Dmel\pdm2Δmiti.hs
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General Information
Symbol
Dmel\pdm2Δmiti.hs
Species
D. melanogaster
Name
FlyBase ID
FBal0039737
Feature type
allele
Associated gene
Dmel\pdm2
Associated Insertion(s)
Carried in Construct
P{hsp70-Δmiti}
Key Links
Transgenic product class
Mutagen
Nature of the Allele
Transgenic product class
Mutagen
in vitro construct
(Bhat and Schedl, 1994)
Progenitor genotype
Carried in construct
P{hsp70-Δmiti}
Cytology
Description

A 1.2kb PstI fragment from the pdm2 cDNA is expressed from an Hsp70 promoter. This fragment lacks usual ATG codon, and if the available internal ATG is used for initiation the resulting product would lack 277 amino acids from the N terminus. Only 8 amino acids upstream of the POU-specific domain will be included in the truncated protein.

(Bhat and Schedl, 1994)
Allele components
Component
Use(s)
Regulatory region(s)
Hsp70
Encoded product / tool
pdm2
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Flies are wild type at 22oC. Cuticle preparations from homozygotes grown at 29oC show 16% of the embryos have segmentation defects, typically in abdominal segments 2 and 6. Temperature shift experiments show that the RP2/sib lineage defect follows a different timecourse than the segmentation defects.

      (Bhat and Schedl, 1994)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      pdm2Δmiti.hs
      Name Synonyms
      Secondary FlyBase IDs
        References (1)