FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\tws59
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General Information
Symbol
Dmel\tws59
Species
D. melanogaster
Name
FlyBase ID
FBal0040058
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Nature of the Allele
Progenitor genotype
Cytology
Description

19bp of the original P{lacW} insert in twsj11C8 remains, and 250bp of intron II of the tws gene is deleted.

Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DNA sequence
Protein sequence
 
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

tws59 homozygotes develop into pharate adults, and many eclose, but immediately fall into the food. Those that do not show entirely uncoordinated movement in walking and overturn. They do not jump or fly. Extra sensory structures form. There are two sets of the shaft and socket instead of a single pair of each. The twin sockets are usually physically connected or fused to each other. Macrochaetae are duplicated or triplicated in mutants. The neuron and sheath cells are probably transformed into support cells. In other cases a single shaft protruded from a large socket with a bottle gourd shape, as for the fusion of two sockets. A minor aspect of the mutant phenotype is bristle loss. Duplication of the taste bristle is very rare. Wing margin chemosensory bristles show no altered morphology, though the long, non-innervated hairs on the posterior wing margin are duplicated.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
Comments
Comments

Phenotype milder than that of tws55 or twsj11C8.

External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (1)
Reported As
Symbol Synonym
tws59
Name Synonyms
Secondary FlyBase IDs
    References (1)