FB2026_03 , released September 17, 2026
Allele: Dmel\wDR18
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General Information
Symbol
Dmel\wDR18
Species
D. melanogaster
Name
FlyBase ID
FBal0040133
Feature type
allele
Associated gene
Dmel\w
Associated Insertion(s)
Carried in Construct
P{wDR18}
Key Links
Transgenic product class
Mutagen
Nature of the Allele
Transgenic product class
Mutagen
in vitro construct
(Lo et al., 1994)
Progenitor genotype
wB4.hs
(Lo et al., 1994)
Carried in construct
P{wDR18}
Cytology
Description

5' splice site mutation. Nucleotide substitutions at positions -1 and +6 of the 5' splice site of the second intron.

(Peng and Mount, 1995)

An Hsp70 promoter is fused upstream of the w transcription unit in which positions -1 and +6 of the 5' splice site of the second intron have been mutated (G to C and T to C nucleotide substitutions respectively). These mutations are expected to weaken base-pairing of the 5' splice site to the 5' end of U1 RNA.

(Lo et al., 1994)
Allele components
Component
Use(s)
Encoded product / tool
w
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Eye colour: apricot. Eye colour: darker with P{U1a-3G} or P{U1b-3G}.

      (Lo et al., 1994)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Enhanced by
      Statement
      Reference

      wDR18 has phenotype, enhanceable by B52ED

      (Peng and Mount, 1995, Mount and Peng, 1994)
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      wDR18
      Name Synonyms
      Secondary FlyBase IDs
        References (3)