FB2026_03 , released September 17, 2026
Allele: Dmel\wa.hs
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General Information
Symbol
Dmel\wa.hs
Species
D. melanogaster
Name
FlyBase ID
FBal0040162
Feature type
allele
Associated gene
Dmel\w
Associated Insertion(s)
Carried in Construct
P{hswa}
Also Known As
P{wa}
Key Links
Transgenic product class
Mutagen
Nature of the Allele
Transgenic product class
Mutagen
in vitro construct
(Kurkulos et al., 1994)
Progenitor genotype
wa
(Kurkulos et al., 1994)
Carried in construct
P{hswa}
Cytology
Description

wa coding region, including the complete copia element, expressed from an Hsp70 promoter.

(Kurkulos et al., 1994)
Allele components
Component
Use(s)
Regulatory region(s)
Hsp70
Encoded product / tool
w
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Eye colour: wa like.

      (Kurkulos et al., 1994)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      Comments
      Comments

      Males carrying P{hswa} and a source of transposase (P\T) have mosaic eyes, due to excision and repair in mitotic cells in the developing eye. Repair events are also occurring in developing mitotic germ line cells in these males, which can be detected by crossing the males to females homozygous for P{hswa}. The female progeny have 3 classes of eye colour; 92% have apricot-coloured eyes (these are probably derived from cells in which P{hswa} did not excise, but some may have resulted from excision followed by repair to restore the complete P{hswa} element). Almost 4% have flat red eyes (more than 90% of the red eyed flies have a single LTR remaining at the copia insertion site in the transgene). About 4% have yellow eyes, corresponding to aberrant repair events that result in the loss of w activity.

      (Adams et al., 2003)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      wa.hs
      Name Synonyms
      Secondary FlyBase IDs
        References (8)