FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Ecol\lacZFas2-A31
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General Information
Symbol
Ecol\lacZFas2-A31
Species
E. coli
Name
FlyBase ID
FBal0040695
Feature type
allele
Associated gene
Ecol\lacZ
Associated Insertion(s)
P{A92}A31
Carried in Construct
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
P-element activity
(Grenningloh et al., 1991, Ghysen and O'Kane, 1989)
Progenitor genotype
Associated Insertion(s)
P{A92}A31
Cytology
Description

Insertion of P-element into Fas2, insertion site is within several hundred nucleotides of the transcriptional start site.

(Grenningloh et al., 1991)
Allele components
Component
Use(s)
Inserted element
P{A92}
Encoded product / tool
lacZ
Tagged with
Tag:NLS(P)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      distribution deduced from reporter
      Stage
      Tissue/Position (including subcellular localization)
      Reference
      embryonic stage
      Malpighian tubule
      (Skaer and Martinez Arias, 1992)
      embryonic stage 11 -- 17
      head
      (Ghysen and O'Kane, 1989)
      ventral neurectoderm | segmentally repeated
      (Ghysen and O'Kane, 1989)
      embryonic stage 12
      larval DA1 motor neuron
      (Grenningloh et al., 1991)
      neuron
      (Grenningloh et al., 1991)
      pCC neuron
      (Grenningloh et al., 1991)
      embryonic stage 13
      vMP2 neuron
      (Grenningloh et al., 1991)
      larval MP1 neuron
      (Grenningloh et al., 1991)
      dMP2 neuron
      (Grenningloh et al., 1991)
      embryonic stage 13 -- 16
      neuron
      • axon
      (Grenningloh et al., 1991)
      embryonic stage 14 -- 16
      larval intersegmental nerve
      (Grenningloh et al., 1991)
      embryonic stage 15
      embryonic/larval posterior spiracle | vicinity of
      (Ghysen and O'Kane, 1989)
      bipolar dendrite neuron | dorsal
      (Ghysen and O'Kane, 1989)
      presumptive embryonic/larval peripheral nervous system | restricted
      (Ghysen and O'Kane, 1989)
      presumptive embryonic/larval central nervous system | restricted
      (Ghysen and O'Kane, 1989)
      embryonic/larval hindgut | restricted
      (Ghysen and O'Kane, 1989)
      Malpighian tubule primordium
      (Ghysen and O'Kane, 1989)
      embryonic stage 16
      larval longitudinal connective
      (Grenningloh et al., 1991)
      Additional Information
      Statement
      Reference

      Enhancer trap staining occurs in the Malpighian tubules throughout their development.

      (Skaer and Martinez Arias, 1992)

      The enhancer trap staining pattern closely resembles the pattern of Fas2 protein expression in the developing nervous system.

      (Grenningloh et al., 1991)
       
      Marker for
      Reflects expression of
      Fas2
      (Grenningloh et al., 1991)
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      Comments
      Comments

      Insertion into the Fas2 gene that does not cause a mutant phenotype.

      (Garcia-Alonso et al., 1995)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      Ecol\lacZA31
      Ecol\lacZFas2-A31
      lacZA31
      Name Synonyms
      Secondary FlyBase IDs
        References (11)