FB2026_02 , released June 18, 2026
Allele: Ecol\lacZeve.MSE
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General Information
Symbol
Ecol\lacZeve.MSE
Species
E. coli
Name
eve minimal stripe element
FlyBase ID
FBal0041346
Feature type
allele
Associated gene
Ecol\lacZ
Associated Insertion(s)
Carried in Construct
P{loxP.MSE-lacZ.lox2272}
P{loxP.MSE-lacZ.loxM2}
P{MSE-lacZ}
Transgenic product class
Mutagen
Nature of the Allele
Transgenic product class
Mutagen
in vitro construct
(Valentine et al., 1998, Dubnicoff et al., 1997, Cai and Levine, 1995, Jiang et al., 1993, Jiang et al., 1992, Small et al., 1992)
Progenitor genotype
Carried in construct
P{loxP.MSE-lacZ.lox2272}
P{loxP.MSE-lacZ.loxM2}
P{MSE-lacZ}
Cytology
Description

The 480bp eve minimal stripe 2 enhancer (MSE) (sequence from -1.55kb to -1.1kb upstream of the eve transcription start site) is fused upstream of eve basal promoter sequence from -42bp, the 100bp eve leader sequence and the first 22 codons of eve protein coding sequence, fused to the lacZ coding sequence at codon 5.

(Small et al., 1992)
Allele components
Component
Use(s)
Encoded product / tool
lacZ
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      distribution deduced from reporter
      Stage
      Tissue/Position (including subcellular localization)
      Reference
      embryonic stage 5
      organism | anterior | restricted

      Comment: anterior stripe

      (Jiang et al., 1992)
      parasegment 3

      Comment: eve stripe 2

      (Kirov et al., 1994)
      organism | anterior
      (Small et al., 1992)
      Additional Information
      Statement
      Reference

      In early embryo, high levels of expression in region corresponding to the second stripe of the wild-type eve expression pattern; very low levels of expression outside the eve stripe 2 region.

      (Jiang et al., 1992)

      In early embryos, expression initially detected in a broad region that spans nearly the entire anterior half of the embryo; after a short time, refined into a stripe. Shown to correspond to the second eve stripe, with some quantitative differences in expression along the dorsal-ventral axis.

      (Small et al., 1992)
       
      Marker for
      Reflects expression of
      eve
      (Kirov et al., 1994, Jiang et al., 1992, Small et al., 1992)
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      Ecol\lacZeve.MSE
      lacZeve.MSE
      Name Synonyms
      eve minimal stripe element
      Secondary FlyBase IDs
        References (13)