FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Ecol\lacZtll.P4
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General Information
Symbol
Ecol\lacZtll.P4
Species
E. coli
Name
FlyBase ID
FBal0042015
Feature type
allele
Associated gene
Ecol\lacZ
Associated Insertion(s)
Carried in Construct
P{tll-lacZ.P4}
Transgenic product class
Mutagen
Nature of the Allele
Transgenic product class
Mutagen
in vitro construct
(Rudolph et al., 1997, Liaw and Lengyel, 1993)
Progenitor genotype
Carried in construct
P{tll-lacZ.P4}
Cytology
Description

tll regulatory sequence from -908bp to +465bp (just 3' of the tll intron) is fused in frame to lacZ.

(Liaw and Lengyel, 1993)
Allele components
Component
Use(s)
Regulatory region(s)
tll_P4
Encoded product / tool
lacZ
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      distribution deduced from reporter (Gal4 UAS)
      Stage
      Tissue/Position (including subcellular localization)
      Reference
      embryonic stage 4
      embryo | posterior | terminal expression pattern
      (Liaw and Lengyel, 1993)
      embryo | anterior | terminal expression pattern
      (Liaw and Lengyel, 1993)
      embryonic stage 5
      embryo | anterior | terminal expression pattern | ventral
      (Liaw and Lengyel, 1993)
      embryo | posterior | terminal expression pattern
      (Liaw and Lengyel, 1993)
      Additional Information
      Statement
      Reference

      Expression at the syncytial and cellular blastoderm stages is observed to be signifcantly lower in anterior cap of the embryo that in the posterior cap. Expression in the posterior cap is lower than that observed for native tll expression. Dorsal stripe expression is not observed in the cellular blastoderm; anterior cap expression is instead shifted to the ventral side of the embryo.

      (Liaw and Lengyel, 1993)
       
      Marker for
      Reflects expression of
      tll
      (Liaw and Lengyel, 1993)
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Ecol\lacZtll.P4
      lacZtll.P4
      Name Synonyms
      Secondary FlyBase IDs
        References (3)