FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\α-Man-IaA122
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General Information
Symbol
Dmel\α-Man-IaA122
Species
D. melanogaster
Name
FlyBase ID
FBal0042353
Feature type
allele
Associated gene
Dmel\α-Man-Ia
Associated Insertion(s)
P{lArB}α-Man-IaA122
Carried in Construct
Key Links
Allele class

hypomorphic allele - genetic evidence

Mutagen
Nature of the Allele
Allele class

hypomorphic allele - genetic evidence

(Kerscher et al., 1995)
Mutagen
P-element activity
(Kerscher et al., 1995)
Progenitor genotype
Associated Insertion(s)
P{lArB}α-Man-IaA122
Cytology
Description

P{lArB} insertion in the 5' region of α-Man-I.

(Kerscher et al., 1995)
Allele components
Component
Use(s)
Inserted element
P{lArB}
Encoded product / tool
lacZ
Tagged with
Tag:NLS(P)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Less than 5% of homozygous embryos display pathfinding errors within the PNS of the intersegmental nerve and abnormal cluster of sensory organs can be found. Homozygous adults display incomplete wing veins L2, L4 and L5, eyes display imperfectly aligned ommatidia and extra bristles.

      (Kerscher et al., 1995)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      Comments
      Comments

      Reduction in the activity of both α-Man-I promoters.

      (Kerscher et al., 1995)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      α-Man-IA122
      α-Man-IaA122
      Name Synonyms
      Secondary FlyBase IDs
        References (1)