FlyBase Allele Report: Dmel\InR[hs.PF]

General Information

Symbol

Dmel\InR^hs.PF

Species

D. melanogaster

Name

heat shock construct of Fernandez

FlyBase ID

FBal0042647

Feature type

allele

Associated gene

Dmel\InR

Associated Insertion(s)

Carried in Construct

P{hs-inr}

Key Links

Transgenic product class

wild_type

(Fernandez et al., 1995)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

wild_type

(Fernandez et al., 1995)

Mutagen

in vitro construct

(Fernandez et al., 1995)

Progenitor genotype

Carried in construct

P{hs-inr}

Cytology

Description

Expression of an 9.5kb EcoRI fragment of InR that expresses a full length protein is driven by an Hsp70 promoter.

(Fernandez et al., 1995)

Allele components

Component

Use(s)

Regulatory region(s)

Hsp70

Encoded product / tool

InR

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Suppressor of

Statement

Reference

InR^hs.PF is a suppressor of mitotic domain 1 | extended germ band stage phenotype of peb^EH704a

(Lamka and Lipshitz, 1999)

InR^hs.PF is a suppressor of embryo | dorsal closure stage phenotype of peb^EH704a

(Lamka and Lipshitz, 1999)

InR^hs.PF is a suppressor of mitotic domain 1 | extended germ band stage phenotype of peb^hnt-1

(Lamka and Lipshitz, 1999)

InR^hs.PF is a suppressor of embryo | dorsal closure stage phenotype of peb^hnt-1

(Lamka and Lipshitz, 1999)

NOT Suppressor of

Statement

Reference

InR^hs.PF is a non-suppressor of amnioserosa phenotype of peb^EH704a

(Lamka and Lipshitz, 1999)

InR^hs.PF is a non-suppressor of amnioserosa phenotype of peb^X001

(Lamka and Lipshitz, 1999)

InR^hs.PF is a non-suppressor of amnioserosa phenotype of peb^hnt-1

(Lamka and Lipshitz, 1999)

Additional Comments

Genetic Interactions

Statement

Reference

Rescues the germ band retraction defect, but not the amnioserosa apoptosis defect, of peb mutant embryos.

(Lamka and Lipshitz, 1999)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

Comments

Same genomic fragment of InR that is carried in plasmid "pRmHa-INR". Rescue the lethality of several InR alleles in trans to Df(3R)e-D7.

(Fernandez et al., 1995)

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

InR^hs.PF

Name Synonyms

heat shock construct of Fernandez

(Fernandez et al., 1995)

Secondary FlyBase IDs

References (2)

Report Sections

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