FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\bwunspecified
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General Information
Symbol
Dmel\bwunspecified
Species
D. melanogaster
Name
FlyBase ID
FBal0042902
Feature type
allele
Associated gene
Dmel\bw
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
    Nature of the Allele
    Allele class
    Mutagen
    Progenitor genotype
    Cytology
    Description

    FlyBase curator comment: this entry is used to capture phenotypic information when the particular allele (or allele combination) used by the author could not be determined but the context of the experiment suggests that the phenotype being described is some kind of loss of function.

    (FlyBase Curators, 2025-)
    Mutations Mapped to the Genome
    Curation Data
    Type
    Location
    Additional Notes
    References
    Variant Molecular Consequences
    Associated Sequence Data
    DDBJ / EMBL / GenBank
    DNA sequence
    Protein sequence
     
    UniProtKB/Swiss-Prot
      UniProtKB/TrEMBL
        Expression Data
        Reporter Expression
        Additional Information
        Statement
        Reference
         
        Marker for
        Reflects expression of
        Reporter construct used in assay
        Human Disease Associations
        Disease Ontology (DO) Annotations
        Models Based on Experimental Evidence ( 0 )
        Disease
        Evidence
        References
        Modifiers Based on Experimental Evidence ( 0 )
        Disease
        Interaction
        References
        Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
         
        Disease-implicated variant(s)
         
        Phenotypic Data
        Phenotypic Class
        Phenotype Manifest In
        Detailed Description
        Statement
        Reference

        A reduced subretinal pigment layer is still present in th eyes of mutant flies.

        (Tomlinson, 2012)

        bwunspecified homozygous female mutants have only 1.1% red pigment in the eye compared to 100% in wild-type flies.

        (Lloyd et al., 2002)

        Brown eyes.

        (Hilliker and Holm, 1975)
        External Data
        Interactions
        Show genetic interaction network for Enhancers & Suppressors
        Phenotypic Class
        NOT Enhanced by
        Statement
        Reference

        bwunspecified has abnormal eye color phenotype, non-enhanceable by Df(1)N-8/we(g)

        (Lloyd et al., 2002)
        Other
        Statement
        Reference

        bwunspecified, g2 has abnormal eye color phenotype

        (Mainx, 1938)
        Phenotype Manifest In
        NOT Enhanced by
        Statement
        Reference

        bwunspecified has pigment cell phenotype, non-enhanceable by Df(1)N-8/we(g)

        (Lloyd et al., 2002)
        Other
        Statement
        Reference

        bwunspecified, g2 has pigment cell phenotype

        (Mainx, 1938)
        Additional Comments
        Genetic Interactions
        Statement
        Reference

        Pigment is absent from the entire eye, including the subretinal region, in bwunspecified bwunspecified double mutants.

        (Tomlinson, 2012)

        bwunspecified/bwunspecified; we(g)/Df(1)N-8 mutants have similar levels of red pigment in the eye to bwunspecified single mutants.

        (Lloyd et al., 2002)

        Eye colour: reddish yellow to brownish rose in combination with g2.

        (Mainx, 1938)
        Xenogenetic Interactions
        Statement
        Reference
        Complementation and Rescue Data
        Comments
        Images (0)
        Mutant
        Wild-type
        Stocks (0)
        Notes on Origin
        Discoverer
        Comments
        Comments

        Exhibits altered distribution of ry protein in adult tissues.

        (Reaume et al., 1991)
        External Crossreferences and Linkouts ( 0 )
        Synonyms and Secondary IDs (2)
        Reported As
        Symbol Synonym
        bw
        (Lloyd et al., 2002)
        bwunspecified
        Name Synonyms
        Secondary FlyBase IDs
          References (7)