FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\cutletclI10
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General Information
Symbol
Dmel\cutletclI10
Species
D. melanogaster
Name
FlyBase ID
FBal0042962
Feature type
allele
Associated gene
Dmel\cutlet
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
    Nature of the Allele
    Allele class
    Mutagen
    Progenitor genotype
    Cytology

    Polytene chromosomes normal.

    (de Belle et al., 1993)
    Description

    Amino acid replacement: K587E.

    (Jaffe and Jongens, 2001)
    Mutations Mapped to the Genome
    Curation Data
    Type
    Location
    Additional Notes
    References
    point_mutation
    2L:3,709,683..3,709,683 [-]
    Nucleotide change:

    A3709683G

    Amino acid change:

    K587E | cutlet-PA

    Reported amino acid change:

    K587E

    Comment:

    Site of nucleotide substitution in mutant inferred by FlyBase based on reported amino acid change.

    (Jaffe and Jongens, 2001)
    Variant Molecular Consequences
    Associated Sequence Data
    DDBJ / EMBL / GenBank
    DNA sequence
    Protein sequence
     
    UniProtKB/Swiss-Prot
      UniProtKB/TrEMBL
        Expression Data
        Reporter Expression
        Additional Information
        Statement
        Reference
         
        Marker for
        Reflects expression of
        Reporter construct used in assay
        Human Disease Associations
        Disease Ontology (DO) Annotations
        Models Based on Experimental Evidence ( 0 )
        Disease
        Evidence
        References
        Modifiers Based on Experimental Evidence ( 0 )
        Disease
        Interaction
        References
        Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
         
        Disease-implicated variant(s)
         
        Phenotypic Data
        Phenotypic Class
        Phenotype Manifest In
        Detailed Description
        Statement
        Reference

        12% of cutletclI10/Df(2L)ed1 animals are viable. The penetrance of the female sterile and rough eye phenotypes in these flies is 100%. The penetrance of the wing phenotype is 30%.

        (Jaffe and Jongens, 2001)

        Visible phenotype when heterozygous with Df(2L)ed1, rough eyes, scalloped trailing and notched end wing margin.

        (de Belle et al., 1993)
        External Data
        Interactions
        Show genetic interaction network for Enhancers & Suppressors
        Phenotypic Class
        Phenotype Manifest In
        Additional Comments
        Genetic Interactions
        Statement
        Reference

        Heterozygotes with fors express an intermediate larval foraging, behavioural phenotype.

        (de Belle et al., 1993)
        Xenogenetic Interactions
        Statement
        Reference
        Complementation and Rescue Data
        Comments
        Images (0)
        Mutant
        Wild-type
        Stocks (0)
        Notes on Origin
        Discoverer
        External Crossreferences and Linkouts ( 0 )
        Synonyms and Secondary IDs (3)
        Reported As
        Symbol Synonym
        cutletcl110
        cutletclI10
        cutleti10
        (Jaffe and Jongens, 2001)
        Name Synonyms
        Secondary FlyBase IDs
          References (3)