FB2026_02 , released June 18, 2026
FB2026_02 , released June 18, 2026
Allele: Dmel\hbC20-hb
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General Information
Symbol
Dmel\hbC20-hb
Species
D. melanogaster
Name
FlyBase ID
FBal0043110
Feature type
allele
Associated gene
Dmel\hb
Associated Insertion(s)
Carried in Construct
P{C20-hb}
Key Links
Genomic Maps

Transgenic product class
genomic_DNA
(Tautz et al., 1987)
wild_type
(Tautz et al., 1987)
Mutagen
Nature of the Allele
Transgenic product class
genomic_DNA
(Tautz et al., 1987)
wild_type
(Tautz et al., 1987)
Mutagen
in vitro construct
(Schroder et al., 1988, Tautz et al., 1987)
Progenitor genotype
Carried in construct
P{C20-hb}
Cytology
Description

The 10kb BamHI fragment contains the entire transcribed region for both the maternal and zygotic promoters, as well as sufficient flanking sequences to drive levels of maternal and early (anterior) zygotic transcription similar to those of the endogenous gene.

(Wharton and Struhl, 1991)

10kb BamHI fragment that includes coding region for hb transcripts.

(Tautz et al., 1987)
Allele components
Component
Use(s)
Regulatory region(s)
hb
Encoded product / tool
hb
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
rescue_region
3R:8,688,813..8,699,434 [-]
Linked to:
BamHI-BamHI restriction fragment
Comment:

partial rescue

(Tautz et al., 1987)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of the hbC20-hb construct in an hb12 genetic background causes fusion of abdominal segments 7 and 8 and defects in the second thoracic segment.

      (Schroder et al., 1988)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Partially rescues

      hbC20-hb partially rescues hbunspecified

      (Tautz et al., 1987)
      Comments

      The hbC20-hb, hb12 mutant phenotype can be rescued by activation of the 2.9kb hb transcript.

      (Schroder et al., 1988)

      Only partially rescues hb mutants: embryos develop a normal head and pro- and meta- thorax, but the mesothorax and posterior hb domain are still abnormal.

      (Tautz et al., 1987)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer

      Tautz.

      (Schroder et al., 1988)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      hbC20-hb
      Name Synonyms
      Secondary FlyBase IDs
      • FBal0034769
      • FBal0034771
      References (4)