FlyBase Allele Report: Dmel\mew[023]

General Information

Symbol

Dmel\mew⁰²³

Species

D. melanogaster

Name

FlyBase ID

FBal0044179

Feature type

allele

Associated gene

Dmel\mew

Associated Insertion(s)

Carried in Construct

Key Links

Allele class

amorphic allele - genetic evidence

Mutagen

X ray

Nature of the Allele

Allele class

amorphic allele - genetic evidence

(Brower et al., 1995)

Mutagen

X ray

(Brower et al., 1995)

Progenitor genotype

Cytology

Description

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

lethal | recessive

(Brower et al., 1995)

Phenotype Manifest In

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Suppressed by

Statement

Reference

if^k27e, mew⁰²³ has midgut primordium phenotype, suppressible by if^Δ.C.UAS/Scer\GAL4^how-24B

(Li et al., 1998)

if^k27e, mew⁰²³ has midgut primordium phenotype, suppressible by if^Δ.m8.UAS/Scer\GAL4^how-24B

(Li et al., 1998)

Other

Statement

Reference

Scer\GAL4^how-24B, if^Δ.C.UAS, mew⁰²³ has midgut primordium phenotype

(Li et al., 1998)

Scer\GAL4^how-24B, if^Δ.m8.UAS, mew⁰²³ has midgut primordium phenotype

(Li et al., 1998)

if^k27e, mew⁰²³ has midgut primordium phenotype

(Li et al., 1998)

if^B4, mew⁰²³ has somatic muscle cell phenotype

(Roote and Zusman, 1995)

if^k27e, mew⁰²³ has somatic muscle cell phenotype

(Roote and Zusman, 1995)

Additional Comments

Genetic Interactions

Statement

Reference

mew⁰²³ if^k27e double mutants have no midgut constrictions. Scer\GAL4^how-24B-mediated expression of if^{Δ.C.Scer\UAS} or if^{Δ.m8.Scer\UAS} rescues initiation of midgut constrictions.

(Li et al., 1998)

Double mutants between mew⁴⁹⁸, mew⁰²³ or mew^M6 and if^k27e or if^B4 do not show the twisted germband, amnioserosal detachment, dorsal movement of germband, dorsal hole and U-shaped embryo phenotypes of mys mutants, but do show early muscle detachments, as seen for mys mutants.

(Roote and Zusman, 1995)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

Kyoto

108251

C(1;Y)6, y¹ w^* P{white-un4}BE1305 mew⁰²³/C(1)RM, y¹ pn¹ v¹; Dp(1;f)y⁺

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

mew⁰²³

Name Synonyms

Secondary FlyBase IDs

References (3)

Report Sections

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