FB2026_02 , released June 18, 2026
Allele: Dmel\nubPrl
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General Information
Symbol
Dmel\nubPrl
Species
D. melanogaster
Name
FlyBase ID
FBal0044227
Feature type
allele
Associated gene
Dmel\nub
Associated Insertion(s)
Carried in Construct
Key Links
Allele class

loss of function allele

Mutagen
    Nature of the Allele
    Allele class

    loss of function allele

    (Ng et al., 1995)
    Mutagen
    Progenitor genotype
    Caused by aberration
    Df(2L)Prl
    Cytology
    Description

    Proximal breakpoint of Df(2L)Prl maps within nub.

    (Yamamoto et al., 2009.2.25)

    The proximal end of Df(2L)Prl shows a complex rearrangement at the nub transcription unit. DNA has been deleted both upstream and downstream of the nub transcription unit, and the remaining portion is inverted with respect to the wild type transcription unit. The protein coding region of the entire β form of the transcript is still present but both of the identified first exons and presumably the transcription start sites have been deleted. In addition, a roo element in inserted into the 3' untranslated region of the transcript.

    (Ng et al., 1995)

    Deletion of the first exon of nub.

    (Yeo et al., 1995)
    Mutations Mapped to the Genome
    Curation Data
    Type
    Location
    Additional Notes
    References
    Variant Molecular Consequences
    Associated Sequence Data
    DDBJ / EMBL / GenBank
    DNA sequence
    Protein sequence
     
    UniProtKB/Swiss-Prot
      UniProtKB/TrEMBL
        Expression Data
        Reporter Expression
        Additional Information
        Statement
        Reference
         
        Marker for
        Reflects expression of
        Reporter construct used in assay
        Human Disease Associations
        Disease Ontology (DO) Annotations
        Models Based on Experimental Evidence ( 0 )
        Disease
        Evidence
        References
        Modifiers Based on Experimental Evidence ( 0 )
        Disease
        Interaction
        References
        Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
         
        Disease-implicated variant(s)
         
        Phenotypic Data
        Phenotypic Class
        Phenotype Manifest In
        Detailed Description
        Statement
        Reference

        Loss of structures from the wing hinge and reduction of the wing blade.

        (Ng et al., 1995)
        External Data
        Interactions
        Show genetic interaction network for Enhancers & Suppressors
        Phenotypic Class
        Phenotype Manifest In
        Additional Comments
        Genetic Interactions
        Statement
        Reference
        Xenogenetic Interactions
        Statement
        Reference
        Complementation and Rescue Data
        Comments
        Images (0)
        Mutant
        Wild-type
        Stocks (2)
        Notes on Origin
        Discoverer
        External Crossreferences and Linkouts ( 0 )
        Synonyms and Secondary IDs (2)
        Reported As
        Symbol Synonym
        nbPrl
        (Gibert et al., 2002)
        nubPrl
        (Yamamoto et al., 2009.2.25)
        Name Synonyms
        Secondary FlyBase IDs
          References (4)