FB2026_03 , released September 17, 2026
Allele: Dmel\otu98
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General Information
Symbol
Dmel\otu98
Species
D. melanogaster
Name
FlyBase ID
FBal0044235
Feature type
allele
Associated gene
Dmel\otu
Associated Insertion(s)
Carried in Construct
P{otu-98}
Key Links
Transgenic product class
wild_type
(Sass et al., 1995)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Sass et al., 1995)
Mutagen
in vitro construct
(Sass et al., 1995)
Progenitor genotype
otu+t5.4
(Sass et al., 1995)
Carried in construct
P{otu-98}
Cytology
Description

AccI genomic fragment of otu containing the alternatively spliced exon 6a is replaced with the corresponding fragment from cDNA that contains exon 6a.

(Sass et al., 1995)
Allele components
Component
Use(s)
Regulatory region(s)
otu
Encoded product / tool
otu
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      Comments
      Comments

      Encodes the otu 98kD isoform. The ability to restore fertility in otu mutants is inversely correlated to the severity of the mutation. Morphological analysis of otu10 P{otu-98} ovaries reveals the construct is incapable of correcting the defects in mutant ovaries, P{otu-98} can only correct defects that occur late in oogenesis.

      (Sass et al., 1995)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      otu98
      Name Synonyms
      Secondary FlyBase IDs
        References (1)