FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\phyl2366
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General Information
Symbol
Dmel\phyl2366
Species
D. melanogaster
Name
FlyBase ID
FBal0044259
Feature type
allele
Associated gene
Dmel\phyl
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
    Nature of the Allele
    Allele class
    Mutagen
    Progenitor genotype
    Cytology
    Description
    Mutations Mapped to the Genome
    Curation Data
    Type
    Location
    Additional Notes
    References
    Variant Molecular Consequences
    Associated Sequence Data
    DDBJ / EMBL / GenBank
    DNA sequence
    Protein sequence
     
    UniProtKB/Swiss-Prot
      UniProtKB/TrEMBL
        Expression Data
        Reporter Expression
        Additional Information
        Statement
        Reference
         
        Marker for
        Reflects expression of
        Reporter construct used in assay
        Human Disease Associations
        Disease Ontology (DO) Annotations
        Models Based on Experimental Evidence ( 0 )
        Disease
        Evidence
        References
        Modifiers Based on Experimental Evidence ( 0 )
        Disease
        Interaction
        References
        Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
         
        Disease-implicated variant(s)
         
        Phenotypic Data
        Phenotypic Class
        Phenotype Manifest In
        Detailed Description
        Statement
        Reference

        phyl2366 homozygous clones in the adult midgut have a significantly decreased number of cells as compared to controls.

        (Yin and Xi, 2018)

        Dead larvae have normally patterned cuticle. Neurons are missing form each of the major groups of PNS neurons in phyl2366/phyl15 embryos.

        (Chang et al., 1995)
        External Data
        Interactions
        Show genetic interaction network for Enhancers & Suppressors
        Phenotypic Class
        Suppressor of
        Statement
        Reference

        phyl[+]/phyl2366 is a suppressor of decreased occurrence of cell division phenotype of CycEJP

        (Brumby et al., 2004)
        Phenotype Manifest In
        NOT Enhancer of
        Statement
        Reference

        phyl[+]/phyl2366 is a non-enhancer of phenotype of Lrev6-3

        (Son and Choi, 2020)
        Suppressor of
        Statement
        Reference

        phyl[+]/phyl2366 is a suppressor of eye disc & S phase phenotype of CycEJP

        (Brumby et al., 2004)

        phyl[+]/phyl2366 is a suppressor of eye phenotype of CycEJP

        (Brumby et al., 2004)

        phyl2366 is a suppressor of phenotype of Raf::tor13D.hs.sev

        (Chang et al., 1995)
        NOT Suppressor of
        Statement
        Reference

        phyl[+]/phyl2366 is a non-suppressor of phenotype of Lrev6-3

        (Son and Choi, 2020)
        Additional Comments
        Genetic Interactions
        Statement
        Reference

        Dominantly suppresses the S phase defects seen in the CycEJP eye disc.

        (Brumby et al., 2004)

        Dominantly suppresses the rough eye and supernumerary R7 phenotype of phl::tor13D.hs.sev. The phyl2366 mutation completely suppresses the supernumerary R7 phenotype of aop and Gap1 mutations.

        (Chang et al., 1995)
        Xenogenetic Interactions
        Statement
        Reference
        Complementation and Rescue Data
        Comments
        Images (0)
        Mutant
        Wild-type
        Stocks (1)
        Notes on Origin
        Discoverer
        External Crossreferences and Linkouts ( 0 )
        Synonyms and Secondary IDs (1)
        Reported As
        Symbol Synonym
        phyl2366
        (Son and Choi, 2020, Yin and Xi, 2018)
        Name Synonyms
        Secondary FlyBase IDs
          References (4)