FlyBase Allele Report: Dmel\put[51]

General Information

Symbol

Dmel\put⁵¹

Species

D. melanogaster

Name

FlyBase ID

FBal0044293

Feature type

allele

Associated gene

Dmel\put

Associated Insertion(s)

P{PZ-Δ.p51}put⁵¹

Carried in Construct

Key Links

Allele class

Mutagen

Nature of the Allele

Allele class

Mutagen

Delta2-3 transposase

(Letsou et al., 1995)

P-element activity

(Simin et al., 1998)

Progenitor genotype

put¹⁰⁴⁶⁰

(Simin et al., 1998, Letsou et al., 1995)

Associated Insertion(s)

P{PZ-Δ.p51}put⁵¹

Cytology

Description

Partial excision of the P{PZ} element, with more than 3kb of the P{PZ} sequences remaining.

(Simin et al., 1998)

Internal deletion of the P-element.

(Letsou et al., 1995)

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

decreased body size (with put¹³⁵)

(McCabe et al., 2004)

lethal

(Letsou et al., 1995)

lethal - all die during embryonic stage | recessive | heat sensitive

(Simin et al., 1998)

some die during embryonic stage | recessive | heat sensitive

(Simin et al., 1998)

visible | recessive

(Simin et al., 1998)

Phenotype Manifest In

embryonic/first instar larval cuticle | dorsal | heat sensitive

(Simin et al., 1998)

embryonic abdominal segment 1 | heat sensitive

(Simin et al., 1998)

embryonic abdominal segment 2 | heat sensitive

(Simin et al., 1998)

embryonic abdominal segment 3 | heat sensitive

(Simin et al., 1998)

embryonic abdominal segment 4 | heat sensitive

(Simin et al., 1998)

embryonic abdominal segment 5 | heat sensitive

(Simin et al., 1998)

embryonic abdominal segment 6 | heat sensitive

(Simin et al., 1998)

embryonic abdominal segment 7 | heat sensitive

(Simin et al., 1998)

embryonic abdominal segment 8 | heat sensitive

(Simin et al., 1998)

embryonic abdominal segment 9 | heat sensitive

(Simin et al., 1998)

embryonic abdominal segment 10 | heat sensitive

(Simin et al., 1998)

embryonic abdominal segment 11 | heat sensitive

(Simin et al., 1998)

somatic muscle cell (with put¹³⁵)

(McCabe et al., 2004)

wing

(Simin et al., 1998)

wing vein

(Simin et al., 1998)

wing vein | ectopic

(Letsou et al., 1995)

Detailed Description

Statement

Reference

put¹³⁵/put⁵¹ animals raised at 18^oC have reduced body and muscle size, but the number of synaptic boutons in these mutants is normal.

(McCabe et al., 2004)

At 18^oC, less than 1% of homozygous embryos have a strong dorsal-open phenotype (large holes in the dorsal cuticle), 31% have an intermediate phenotype (the dorsal cuticle is noticeably reduced, and there is increased curvature in the abdominal segments, resulting in a "tail-up" phenotype) and 69% have a weak phenotype. The prevalence of the strong dorsal-open phenotype is increased at 29^oC. put¹⁰/put⁵¹ adults are viable, and sometimes show defects in wing venation.

(Simin et al., 1998)

Heterozygotes with put¹⁰⁴⁶⁰ are lethal at high temperatures, at low temperatures individuals survive and exhibit ectopic wing venation in the region of the posterior cross vein. Escaper females produce ventralised embryos.

(Letsou et al., 1995)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Fails to complement

put¹⁰⁴⁶⁰

(Simin et al., 1998)

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

Selected as: ry^- excision allele.

(Simin et al., 1998)

Comments

Three classes of put allele can be identified with respect to decreasing severity of wing venation phenotypes with put¹⁰ : Class I (put¹⁰⁴⁶⁰ = put⁶²) > Class II (put⁵¹ = put⁸⁸ = put¹³⁵) > Class III (put¹⁰ = put²⁴ = put⁹⁷).

(Simin et al., 1998)

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (4)

Reported As

Symbol Synonym

punt⁵¹

(Simin et al., 1998)

punt^P51

(Marques et al., 2002)

put⁵¹

put^Δ51

(McCabe et al., 2004)

Name Synonyms

Secondary FlyBase IDs

References (4)

Report Sections

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