FlyBase Allele Report: Dmel\shn[k00401]

General Information

Symbol

Dmel\shn^k00401

Species

D. melanogaster

Name

FlyBase ID

FBal0044299

Feature type

allele

Associated gene

Dmel\shn

Associated Insertion(s)

P{lacW}shn^k00401

Carried in Construct

Key Links

Genomic Maps

JBrowse

Allele class

Mutagen

P-element activity

Nature of the Allele

Allele class

Mutagen

P-element activity

Progenitor genotype

Associated Insertion(s)

P{lacW}shn^k00401

Cytology

Description

Allele components

Component

Use(s)

Inserted element

P{lacW}

enhancer trap

Encoded product / tool

lacZ

reporter enzyme

Tagged with

Tag:NLS(P)

nuclear protein localization tag

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

transposable_element_insertion_site

2R:11,197,366..11,197,366 [+]

(Dworkin and Gibson, 2006, Spradling et al., 1999, BDGP Project Members, 1994-1999)

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal neuroanatomy

(Rusten et al., 2002)

lethal | recessive

(Dworkin and Gibson, 2006, Spradling et al., 1999, BDGP Project Members, 1994-1999)

Phenotype Manifest In

embryo | dorsal closure stage

(Rusten et al., 2002)

embryonic abdominal dorsal sensory organ precursor cluster

(Rusten et al., 2002)

embryonic abdominal lateral sensory organ precursor cluster

(Rusten et al., 2002)

presumptive embryonic/larval peripheral nervous system

(Rusten et al., 2002)

Detailed Description

Statement

Reference

Homozygous embryos fail to undergo dorsal closure and show severe defects in the development of the peripheral nervous system (PNS); fewer neurons are present, especially in the dorsal and lateral PNS clusters.

(Rusten et al., 2002)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Fails to complement

shn^unspecified

(Dworkin and Gibson, 2006)

shn⁰⁴⁷³⁸

(BDGP Project Members, 1994-1999)

shn^rP005

(BDGP Project Members, 1994-1999)

shn^k04412

(BDGP Project Members, 1994-1999)

shn⁰⁵⁵⁹⁵

(BDGP Project Members, 1994-1999)

Comments

Images (0)

Mutant

Wild-type

Stocks (2)

Bloomington

10478

y¹ w^67c23; P{lacW}shn^k00401/CyO

Kyoto

111126

y^d2 w¹¹¹⁸ P{ey-FLP.N}2 P{5xglBS-lacZ.38-1}TPN1; P{neoFRT}42D P{lacW}shn^k00401 /CyO y⁺

Notes on Origin

Discoverer

I. Kiss.

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (4)

Reported As

Symbol Synonym

k00401

(Dworkin and Gibson, 2006)

l(2)k00401

(Spradling et al., 1999)

quo^k00401

shn^k00401

Name Synonyms

Secondary FlyBase IDs

References (6)

Report Sections

Open Close