FlyBase Allele Report: Dmel\svp[hs.ro1]

General Information

Symbol

Dmel\svp^hs.ro1

Species

D. melanogaster

Name

FlyBase ID

FBal0044363

Feature type

allele

Associated gene

Dmel\svp

Associated Insertion(s)

Carried in Construct

P{ro-svp1}

Key Links

Transgenic product class

cDNA

(Kramer et al., 1995)

wild_type

(Kramer et al., 1995)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

cDNA

(Kramer et al., 1995)

wild_type

(Kramer et al., 1995)

Mutagen

in vitro construct

(Kramer et al., 1995)

Progenitor genotype

Carried in construct

P{ro-svp1}

Cytology

Description

Construct: Ectopic expression of svp cDNA1 is driven by 2.8kb ro enhancer fragment fused at position -254 to the Hsp70 promoter.

(Kramer et al., 1995)

Allele components

Component

Use(s)

Regulatory region(s)

Encoded product / tool

svp

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

eye photoreceptor cell

(Kramer et al., 1995)

Detailed Description

Statement

Reference

Adults exhibit dose-dependent roughening of the eye surface due to loss of one or more outer photoreceptors from many of the ommatidia because of failure to initiate neuronal differentiation. Receptor cells 2 and 5 lose aspects of their photoreceptor subtype identity while remaining neuronal.

(Kramer et al., 1995)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Enhanced by

Statement

Reference

svp^hs.ro1 has phenotype, enhanceable by Egfr^A3

(Kramer et al., 1995)

svp^hs.ro1 has phenotype, enhanceable by Egfr^f3

(Kramer et al., 1995)

svp^hs.ro1 has phenotype, enhanceable by Ras85D^C33

(Kramer et al., 1995)

svp^hs.ro1 has phenotype, enhanceable by Sos^e4G

(Kramer et al., 1995)

svp^hs.ro1 has phenotype, enhanceable by csw^Esev1A-eOP

(Kramer et al., 1995)

svp^hs.ro1 has phenotype, enhanceable by drk^e0A

(Kramer et al., 1995)

svp^hs.ro1 has phenotype, enhanceable by Raf^LQ129

(Kramer et al., 1995)

Suppressed by

Statement

Reference

svp^hs.ro1 has phenotype, suppressible by Sos^F1

(Kramer et al., 1995)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

Comments

Direct transcription in R2/R5/R3/R4 cells.

(Kramer et al., 1995)

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

svp^hs.ro1

Name Synonyms

Secondary FlyBase IDs

References (3)

Report Sections

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