FB2026_03 , released September 17, 2026
Allele: Dmel\Ras85DV12.sev.3sE
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General Information
Symbol
Dmel\Ras85DV12.sev.3sE
Species
D. melanogaster
Name
FlyBase ID
FBal0045026
Feature type
allele
Associated gene
Dmel\Ras85D
Associated Insertion(s)
Carried in Construct
P{sevRas1.V12(3sE)}
Key Links
Transgenic product class
missense_variant
(Fortini et al., 1992)
Mutagen
Nature of the Allele
Transgenic product class
missense_variant
(Fortini et al., 1992)
Mutagen
in vitro construct
(Fortini et al., 1992)
Progenitor genotype
Carried in construct
P{sevRas1.V12(3sE)}
Cytology
Description

The sev promoter is fused upstream of sequence that encodes an activated form of Ras85D (amino acid 12 has been mutated to Val). Three copies of the sev enhancer are present downstream of the Ras85D coding sequence.

(Fortini et al., 1992)
Allele components
Component
Use(s)
Regulatory region(s)
sev
Encoded product / tool
Ras85D
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Rough eye phenotype, most ommatidia contain supernumerary R7 cells, aberrant packing and rotation of ommatidia, occasional extra or missing R1-R6 cells and missing pigment cells.

      (Fortini et al., 1992)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      Ras85DV12.sev.3sE
      Name Synonyms
      Secondary FlyBase IDs
        References (1)