Neurons in culture derived from dnc^unspecified mutants display a suppression of neuronal response amplitude and a change in response kinetics to high K+ depolarisation with 30 seconds of high K⁺ stimulation. With 60 seconds of high K⁺ stimulation, the response approaches that of wild-type levels. dnc^unspecified does not alter response duration within the growth cone, whereas the duration is increased within the soma in cultured embryonic neurons. dnc^unspecified does not alter the basal Ca²⁺ levels in either region. Release of Ca²⁺ from intracellular stores or the complex electrical activity cause by ion channel interactions can lead to multiple peaks during the high K⁺ response. The prevalence of a shoulder or second peak during the high K⁺ response is suppressed in dnc^unspecified mutants (to a greater extent than rut^unspecified mutants).

In homozygotes no effect is seen on the amplitude of the synchronous oscillation of intracellular calcium concentration seen in wild type Kenyon cells.

Mutant flies have a limited ability to focus attention on specific visual figures in a visual stimulus assay.

Flies show abnormally low habituation to sucrose stimuli applied to the tarsus.