FB2026_02 , released June 18, 2026
Allele: Dmel\faxM34
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General Information
Symbol
Dmel\faxM34
Species
D. melanogaster
Name
FlyBase ID
FBal0045633
Feature type
allele
Associated gene
Dmel\fax
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
X ray
(Hill et al., 1995)
ethyl methanesulfonate
(Hill et al., 1995)
Progenitor genotype
Cytology
Description

Internal deletion, 5' breakpoint is just after Glu139 and the 3' breakpoint residing in the first intron. The result is an inframe mRNA transcript encoding an internally deleted protein.

(Hill et al., 1995)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Homozygous adults show no obvious mutant phenotype.

      (Hill et al., 1995)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Enhancer of
      Statement
      Reference

      faxM34 is an enhancer of phenotype of Abl1

      (Hill et al., 1995)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      faxM34 Abl1/Df(3L)st-j7 individuals are lethal due to disruptions in the CNS longitudinal and commissural axons. One copy of Abl+mTnabl-lys moderately rescues and one copy of Abl+mTnabl completely rescues the lethality. faxM34 Abl1/Df(3L)st-g24 individuals are weakly viable, this semi-lethality can be alleviated by one copy of Abl+mTnabl.

      (Hill et al., 1995)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      Comments
      Comments

      "X ray" was stated as tentative. "ethyl methanesulfonate" was stated as tentative. Haploinsufficiency dependent upon an Abl mutant background (HDA).

      (Hill et al., 1995)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      faxM34
      Name Synonyms
      Secondary FlyBase IDs
        References (1)