FB2026_02 , released June 18, 2026
Allele: Dmel\ftzK
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General Information
Symbol
Dmel\ftzK
Species
D. melanogaster
Name
FlyBase ID
FBal0045736
Feature type
allele
Associated gene
Dmel\ftz
Associated Insertion(s)
Carried in Construct
P{ftzK}
Key Links
Transgenic product class
Mutagen
Nature of the Allele
Transgenic product class
Mutagen
in vitro construct
(Doe et al., 1988)
Progenitor genotype
ftz+t10.8
(Doe et al., 1988)
Carried in construct
P{ftzK}
Cytology
Description

Construct: Deletion of 2.8kb fragment containing the neurogenic element and an adjacent 0.95kb fragment dispensable for normal ftz expression.

(Doe et al., 1988)
Allele components
Component
Use(s)
Encoded product / tool
ftz
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      P{ftzK}; ftz13 embryos fail to express ftz in the CNS and have a normal or only mildly defective epidermal development (FBrf0049007).

      (Yeo et al., 1995)

      P{ftzK}; ftz11/ftz13 individuals die as embryos or larvae. P{ftzK}; ftz11/ftz13 embryos are identified by weak segmentation defects in the CNS.

      (Doe et al., 1988)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      ftzK rescues ftz13

      (Heffer et al., 2013)
      Comments

      Expression of ftzK in a ftz13 background rescues the segmentation defects but does not rescue CNS function, as illustrated by the RP2 neurons, which fail to develop.

      (Heffer et al., 2013)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      Comments
      Comments

      ftz promoter fragment is the same as that used in the P{ftz/lacD} construct (FBrf0045785).

      (Doe et al., 1988)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      ftzK
      (Heffer et al., 2013)
      Name Synonyms
      Secondary FlyBase IDs
        References (3)