FB2026_02 , released June 18, 2026
FB2026_02 , released June 18, 2026
Allele: Dmel\lup-2HB267
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General Information
Symbol
Dmel\lup-2HB267
Species
D. melanogaster
Name
FlyBase ID
FBal0046126
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Nature of the Allele
Progenitor genotype
Cytology
Description
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DNA sequence
Protein sequence
 
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

The kl-3 Y chromosome loop is absent in lup-2HB267 mutant primary spermatocytes. This phenotype is also present in lup-2HB267/Df(3R)P-10 mutants. In the axoneme of lup-2HB267 sperm flagella, the outer dynein arms are generally absent and the inner dynein arm complement is incomplete. Additionally, there are further defects in axonemal organization, such as a tendency for the axoneme to fragment longitudinally, an ectopic assembly of microtubular doublets within the cytoplasm and the presence of supernumerary central tubules, which appear to assemble from pre-existing microtubules.

Lack kl-3 Y chromosome lampbrush loop.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer

J.H.P. Hackstein

External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (3)
Reported As
Symbol Synonym
lup-2HB267
ms(3)HB2671
Name Synonyms
Secondary FlyBase IDs
    References (2)