FB2026_02 , released June 18, 2026
Allele: Dmel\kl-3104b
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General Information
Symbol
Dmel\kl-3104b
Species
D. melanogaster
Name
FlyBase ID
FBal0046129
Feature type
allele
Associated gene
Dmel\kl-3
Associated Insertion(s)
P{PZ}kl-3104b
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
P-element activity
(Zhang, 1996.4.28)
Progenitor genotype
Associated Insertion(s)
P{PZ}kl-3104b
Cytology
Description
Allele components
Component
Use(s)
Inserted element
P{PZ}
Encoded product / tool
lacZ
Tagged with
Tag:NLS(P)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Normal looking individualisation complexes (ICs) are seen in the testes of X/kl-3104b males. Spermatid tails show irregularities.

      (Timakov and Zhang, 2000)

      A few males produce a small number of progeny (average 0.1 progeny/male). Male sterile in combination with Ts(1Lt;YSt)W27, Ts(1Lt;YSt)E15 or Ts(1Lt;YSt)F12. Male fertile in combination with Ts(1Lt;YSt)V24. kl-3104b testes show degradation in the basal testicular region. Sperm are absent from the seminal vesicles. Postmeiotic nuclei show almost normal nuclear condensation, except for the appearance of occasional singular needle-shaped nuclear heads. The organised bundles of the elongated sperm heads are eventually disintegrated in the basal region of the testis before the spermatids reach maturity. Defects are seen in the flagellar axoneme.

      (Zhang and Stankiewicz, 1998)

      Late spermatogenesis is disrupted, defective sperm are not mobile.

      (Zhang et al., 1996)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      Comments
      Comments

      Male sterile phenotype can be reverted in the presence of a transposase source.

      (Zhang and Stankiewicz, 1998)

      Revertants prove the single P{PZ} insertion is the cause of the male sterile phenotype.

      (Zhang et al., 1996)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      kl-3104b
      ms(Y)104b
      (Zhang and Stankiewicz, 1998)
      ms(Y)104b104b
      Name Synonyms
      Secondary FlyBase IDs
        References (4)