FlyBase Allele Report: Dmel\veg[k17010]

General Information

Symbol

Dmel\veg^k17010

Species

D. melanogaster

Name

FlyBase ID

FBal0046662

Feature type

allele

Associated gene

veg

Associated Insertion(s)

P{lacW}veg^k17010

Carried in Construct

Key Links

Allele class

Mutagen

P-element activity

Nature of the Allele

Allele class

Mutagen

P-element activity

(Kania et al., 1995)

Progenitor genotype

Associated Insertion(s)

P{lacW}veg^k17010

Cytology

Description

Allele components

Component

Use(s)

Inserted element

P{lacW}

enhancer trap

Encoded product / tool

lacZ

reporter enzyme

Tagged with

Tag:NLS(P)

nuclear protein localization tag

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

lethal | recessive

(Spradling et al., 1999)

lethal - all die during embryonic stage | recessive

(Kania et al., 1995)

some die during embryonic stage | recessive

(Kania et al., 1995)

Phenotype Manifest In

presumptive embryonic/larval central nervous system

(Kania et al., 1995)

presumptive embryonic/larval peripheral nervous system

(Kania et al., 1995)

Detailed Description

Statement

Reference

Homozygous embryos exhibit severe loss of neurons in the PNS and CNS phenotype.

(Kania et al., 1995)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Complements

L⁰³⁵⁶³

(BDGP Project Members, 1994-1999)

Sema2a⁰³⁰²¹

(BDGP Project Members, 1994-1999)

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

Kyoto

103060

y¹ w^67c23 ; P{lacW}veg^k17010 / CyO

Notes on Origin

Discoverer

Comments

Lethality not revertible with excision of the P{lacW} insert. Chromosome may also carry other mutations that cause embryonic defects.

(Kania et al., 1995)

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (3)

Reported As

Symbol Synonym

170/10

(Kania et al., 1995)

l(2)k17010

(Spradling et al., 1999)

veg^k17010

Name Synonyms

Secondary FlyBase IDs

References (3)

Report Sections

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