FlyBase Allele Report: Dmel\w[BgB+173]

General Information

Symbol

Dmel\w^BgB+173

Species

D. melanogaster

Name

FlyBase ID

FBal0046735

Feature type

allele

Associated gene

Dmel\w

Associated Insertion(s)

Carried in Construct

P{BgB-(+173)miniW}

Key Links

Transgenic product class

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

Mutagen

in vitro construct

(Bhadra et al., 1997, Bhadra et al., 1997, Qian et al., 1992)

Progenitor genotype

w^+mSC

(Qian et al., 1992)

w^-17

(Bhadra et al., 1997)

Carried in construct

P{BgB-(+173)miniW}

Cytology

Description

Deletion of 5' sequences to +174bp.

(Bhadra et al., 1997)

Construct: Fusion of the w eye enhancer sequence upstream of w 5' flanking sequences.

(Bhadra et al., 1997)

Deletion of 5' regulatory site at +174bp.

(Bhadra and Birchler, 1996)

Deletion of 5' region and some untranslated leader region with the effect that the BgB enhancer is juxtaposed with position +173, 4bp before the AUG initiation codon.

(Qian et al., 1992)

Allele components

Component

Use(s)

Encoded product / tool

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

visible | recessive

(Qian et al., 1992)

Phenotype Manifest In

pigment cell

(Qian and Pirrotta, 1995)

testis pigment cell

(Qian et al., 1992)

Detailed Description

Statement

Reference

Shows greater dosage compensation in X chromosomal than in autosomal sites.

(Qian and Pirrotta, 1995)

Eye colour: dull red. Testis colour: colourless.

(Qian et al., 1992)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

NOT Enhanced by

Statement

Reference

w^BgB+173 has phenotype, non-enhanceable by Low¹

(Bhadra et al., 1997)

w^BgB+173 has phenotype, non-enhanceable by Mow^gamma

(Bhadra and Birchler, 1996)

NOT suppressed by

Statement

Reference

w^BgB+173 has phenotype, non-suppressible by Low¹

(Bhadra et al., 1997)

w^BgB+173 has phenotype, non-suppressible by Mow^gamma

(Bhadra and Birchler, 1996)

Additional Comments

Genetic Interactions

Statement

Reference

The eye colour of flies carrying w^BgB+173 on either the X chromosome or an autosome is unaffected by a single copy of Low¹.

(Bhadra et al., 1997)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

Comments

Protein fails to interact with Ufo¹.

(Bhadra et al., 1997)

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

w⁺¹⁷⁴

w^BgB+173

Name Synonyms

Secondary FlyBase IDs

FBal0060843

References (5)

Report Sections

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