FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\wZ4-17
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General Information
Symbol
Dmel\wZ4-17
Species
D. melanogaster
Name
FlyBase ID
FBal0046781
Feature type
allele
Associated gene
Dmel\w
Associated Insertion(s)
Carried in Construct
P{Z4(-17)miniW}
Key Links
Transgenic product class
Mutagen
Nature of the Allele
Transgenic product class
Mutagen
in vitro construct
(Bhadra et al., 1997, Bhadra et al., 1997, Qian and Pirrotta, 1995)
Progenitor genotype
w-17
(Bhadra et al., 1997, Qian and Pirrotta, 1995)
Carried in construct
P{Z4(-17)miniW}
Cytology
Description

5' sequences are deleted up to -17bp and a 40bp synthetic oligonucleotide containing four z protein binding sites is fused to the 5' end.

(Bhadra et al., 1997)

Construct: w promoter sequences up to 17bp drive w gene expression.

(Bhadra et al., 1997)

Deletion of 5' regulatory site at -17bp and the addition of tetramer of z binding site.

(Bhadra and Birchler, 1996)

A 40bp synthetic oligonucleotide containing four z protein binding sites is fused to the 5' end of w-17.

(Qian and Pirrotta, 1995)
Allele components
Component
Use(s)
Encoded product / tool
w
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Decrease in wild type eye pigment in the presence of Mowgamma.

      (Bhadra and Birchler, 1996)

      Eye colour: pigmented.

      (Qian and Pirrotta, 1995)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      NOT Enhanced by
      Statement
      Reference

      wZ4-17 has phenotype, non-enhanceable by Low1

      (Bhadra et al., 1997)
      NOT suppressed by
      Statement
      Reference

      wZ4-17 has phenotype, non-suppressible by Low1

      (Bhadra et al., 1997)
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      Comments
      Comments

      Shows greater dosage compensation in X chromosomal than in autosomal sites.

      (Qian and Pirrotta, 1995)

      Protein fails to interact with Ufo1.

      (Bhadra et al., 1997)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      wZ4-17
      Name Synonyms
      Secondary FlyBase IDs
        References (4)