FlyBase Allele Report: Mmus\Pax6[UAS.cHa]

General Information

Symbol

Mmus\Pax6^UAS.cHa

Species

M. musculus

Name

Saccharomyces cerevisiae UAS construct a of Halder

FlyBase ID

FBal0047100

Feature type

allele

Associated gene

Mmus\Pax6

Associated Insertion(s)

Carried in Construct

P{UAS-Pax-6.mus}

Also Known As

UAS-Pax6

Transgenic product class

cDNA

(Halder et al., 1995)

wild_type

(Halder et al., 1995)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

cDNA

(Halder et al., 1995)

wild_type

(Halder et al., 1995)

Mutagen

in vitro construct

(Halder et al., 1995)

Progenitor genotype

Carried in construct

P{UAS-Pax-6.mus}

Cytology

Description

Expression of a full length Mmus\Pax6 cDNA is governed by UAS.

(Halder et al., 1995)

Allele components

Component

Use(s)

Regulatory region(s)

UAS

binary expression system - regulatory region

Encoded product / tool

Mmus\Pax6

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

visible, with Scer\GAL4^30A

(Tanaka-Matakatsu et al., 2014)

visible, with Scer\GAL4^upd1-E132

(Halder et al., 1995)

Phenotype Manifest In

antenna, with Scer\GAL4^upd1-E132

(Halder et al., 1995)

eye | ectopic, with Scer\GAL4^30A

(Tanaka-Matakatsu et al., 2014)

haltere, with Scer\GAL4^upd1-E132

(Halder et al., 1995)

leg, with Scer\GAL4^upd1-E132

(Halder et al., 1995)

wing, with Scer\GAL4^upd1-E132

(Halder et al., 1995)

wing hinge, with Scer\GAL4^30A

(Tanaka-Matakatsu et al., 2014)

Detailed Description

Statement

Reference

Expression of Mmus\Pax6^Scer\UAS.cHa under the control of Scer\GAL4^30A can induce a small amount of ectopic eye tissue on wing hinges.

(Tanaka-Matakatsu et al., 2014)

Overexpression of Mmus\Pax6^Scer\UAS.cHa, under the control of Scer\GAL4^dpp.blk1, has little or no effect on wing outgrowths in the wing disc.

(Dominguez et al., 2004)

When expressed via Scer\GAL4^E132, ectopic eyes are induced in the wing, leg, antenna and haltere. Phenotype of ectopic eyes is very similar to those of ey^Scer\UAS.cHa.

(Halder et al., 1995)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhanced by

Statement

Reference

Mmus\Pax6^UAS.cHa, Scer\GAL4^30A has visible phenotype, enhanceable by da^UAS.cGa, Scer\GAL4^30A

(Tanaka-Matakatsu et al., 2014)

Mmus\Pax6^UAS.cHa, Scer\GAL4^30A has visible phenotype, enhanceable by da^{da-da.cTa.UAS}, Scer\GAL4^30A

(Tanaka-Matakatsu et al., 2014)

Mmus\Pax6^UAS.cHa, Scer\GAL4^30A has visible phenotype, enhanceable by da^da-da.UAS, Scer\GAL4^30A

(Tanaka-Matakatsu et al., 2014)

Phenotype Manifest In

Enhanced by

Statement

Reference

Mmus\Pax6^UAS.cHa, Scer\GAL4^30A has wing hinge phenotype, enhanceable by da^UAS.cGa, Scer\GAL4^30A

(Tanaka-Matakatsu et al., 2014)

Mmus\Pax6^UAS.cHa, Scer\GAL4^30A has eye | ectopic phenotype, enhanceable by da^UAS.cGa, Scer\GAL4^30A

(Tanaka-Matakatsu et al., 2014)

Mmus\Pax6^UAS.cHa, Scer\GAL4^30A has wing hinge phenotype, enhanceable by da^{da-da.cTa.UAS}, Scer\GAL4^30A

(Tanaka-Matakatsu et al., 2014)

Mmus\Pax6^UAS.cHa, Scer\GAL4^30A has eye | ectopic phenotype, enhanceable by da^{da-da.cTa.UAS}, Scer\GAL4^30A

(Tanaka-Matakatsu et al., 2014)

Mmus\Pax6^UAS.cHa, Scer\GAL4^30A has wing hinge phenotype, enhanceable by da^da-da.UAS, Scer\GAL4^30A

(Tanaka-Matakatsu et al., 2014)

Mmus\Pax6^UAS.cHa, Scer\GAL4^30A has eye | ectopic phenotype, enhanceable by da^da-da.UAS, Scer\GAL4^30A

(Tanaka-Matakatsu et al., 2014)

NOT suppressed by

Statement

Reference

Mmus\Pax6^UAS.cHa has eye | ectopic phenotype, non-suppressible by Scer\GAL4^dpp.blk1, ey²/ey²

(Punzo et al., 2004)

Mmus\Pax6^UAS.cHa has eye | ectopic phenotype, non-suppressible by Scer\GAL4^dpp.blk1, ey^J5.71/ey^J5.71

(Punzo et al., 2004)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Co-expression of da^Scer\UAS.cGa results in increased size of ectopic eyes induced by Scer\GAL4^30A>Mmus\Pax6^Scer\UAS.cHa.

Co-expression of da^{da-da.cTa.Scer\UAS} results in increased size of ectopic eyes induced by Scer\GAL4^30A>Mmus\Pax6^Scer\UAS.cHa.

Co-expression of da^{da-da.Scer\UAS} results in increased size of ectopic eyes induced by Scer\GAL4^30A>Mmus\Pax6^Scer\UAS.cHa.

(Tanaka-Matakatsu et al., 2014)

The ectopic eyes seen in Mmus\Pax6^Scer\UAS.cHa; Scer\GAL4^dpp.blk1 flies are not suppressed by ey²/ey² or ey^J5.71/ey^J5.71.

(Punzo et al., 2004)

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (6)

Reported As

Symbol Synonym

Mmus\Pax6^Scer\UAS.cHa

Mmus\Pax6^UAS.cHa

Mus\Pax6^Scer\UAS.cHa

Mus\Pax6^UAS.cHa

Mus\Sey^UAS.cHa

Name Synonyms

Saccharomyces cerevisiae UAS construct a of Halder

(Halder et al., 1995)

Secondary FlyBase IDs

References (5)

Report Sections

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