FB2026_03 , released September 17, 2026
Allele: Ecol\lacZct.D
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General Information
Symbol
Ecol\lacZct.D
Species
E. coli
Name
FlyBase ID
FBal0047635
Feature type
allele
Associated gene
Ecol\lacZ
Associated Insertion(s)
Carried in Construct
P{cutD-hsp70-lacZ}
Also Known As
ct-D2.3
Transgenic product class
Mutagen
Nature of the Allele
Transgenic product class
Mutagen
in vitro construct
(Jack and DeLotto, 1995)
Progenitor genotype
Ecol\lacZHsp70Bb.HZ50
(Jack and DeLotto, 1995)
Carried in construct
P{cutD-hsp70-lacZ}
Cytology
Description

3.8kb HindIII fragment of the ct regulatory region is fused upstream of a minimal Hsp70 promoter followed by lacZ reporter sequence.

(Jack and DeLotto, 1995)
Allele components
Component
Use(s)
Regulatory region(s)
ct_cutD
Encoded product / tool
lacZ
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      distribution deduced from reporter
      Stage
      Tissue/Position (including subcellular localization)
      Reference
      embryonic stage
      Malpighian tubule
      (Jack and DeLotto, 1995)
      ventral pharyngeal sense organ
      (Jack and DeLotto, 1995)
      larval antenno-maxillary sensory complex
      (Jack and DeLotto, 1995)
      presumptive embryonic/larval central nervous system | restricted
      (Jack and DeLotto, 1995)
      embryonic/larval labral segment sense organ
      (Jack and DeLotto, 1995)
      embryonic stage -- larval stage
      fascicle
      (Jack and DeLotto, 1995)
      Additional Information
      Statement
      Reference

      A 3.8kb HindIII fragment of the ctregulatory region fused to a minimal Hsp70 promoter drives expression ofEcollacZ in embryonic and larval tissues. In the embryonic central nervoussystem (CNS), EcollacZ expression is visible in 4 cells per segment. In theembryonic peripheral nervous system (PNS), EcollacZ is expressed in theantenno-maxillary organs, the hypophysis, and the epiphysis. The ventralend of fascicles which carry axons from the PNS into the ganglia of theCNS express EcollacZ in both embryos and late third instar larvae. A subsetof cells in the internal portion of the posterior spiracles of the embryoexpress EcollacZ. EcollacZ staining in the Malpighian tubules is weak.

      (Jack and DeLotto, 1995)
       
      Marker for
      Reflects expression of
      ct
      (Jack and DeLotto, 1995)
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Ecol\lacZct.D
      lacZct.D
      Name Synonyms
      Secondary FlyBase IDs
        References (4)