Construct: Expression of a 3.2kb Con cDNA that contains the entire open reading frame is driven by a minimal Hsp70 promoter and influenced by a 6.5kb Tl enhancer and SV40 polyadenylation site.
Expression alters SNb development, their morphology and trajectory are altered when they encounter ectopic Con expressing ventral muscles. RP3 and RP1 growth cone behaviour is also altered.