FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\ER3-3XE-571
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General Information
Symbol
Dmel\ER3-3XE-571
Species
D. melanogaster
Name
FlyBase ID
FBal0048721
Feature type
allele
Associated gene
ER3-3
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
    Nature of the Allele
    Allele class
    Mutagen
    Progenitor genotype
    Cytology
    Description
    Mutations Mapped to the Genome
    Curation Data
    Type
    Location
    Additional Notes
    References
    Variant Molecular Consequences
    Associated Sequence Data
    DDBJ / EMBL / GenBank
    DNA sequence
    Protein sequence
     
    UniProtKB/Swiss-Prot
      UniProtKB/TrEMBL
        Expression Data
        Reporter Expression
        Additional Information
        Statement
        Reference
         
        Marker for
        Reflects expression of
        Reporter construct used in assay
        Human Disease Associations
        Disease Ontology (DO) Annotations
        Models Based on Experimental Evidence ( 0 )
        Disease
        Evidence
        References
        Modifiers Based on Experimental Evidence ( 0 )
        Disease
        Interaction
        References
        Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
         
        Disease-implicated variant(s)
         
        Phenotypic Data
        Phenotypic Class
        Phenotype Manifest In
        Detailed Description
        Statement
        Reference
        External Data
        Interactions
        Show genetic interaction network for Enhancers & Suppressors
        Phenotypic Class
        Suppressor of
        Statement
        Reference

        ER3-3XE-571 is a suppressor of lethal phenotype of Raf12

        (Karim et al., 1996)
        Phenotype Manifest In
        Enhancer of
        Statement
        Reference

        ER3-3XE-571 is an enhancer of phenotype of Ras85DV12.sev

        (Karim et al., 1996)
        Suppressor of
        Statement
        Reference

        ER3-3XE-571 is a suppressor of eye phenotype of Raf12

        (Karim et al., 1996)
        Additional Comments
        Genetic Interactions
        Statement
        Reference

        Enhances the rough eye phenotype of Ras85DV12.sev. Slightly suppresses the phenotype of Ras85DN17.sev. Enhances the phenotype of phl::tor13D.hs.sev. Enhances the phenotype of Ras85D::Src64BV12.ΔCAAX.sev. Suppresses the lethality of phl12. Suppresses the phl12 eye phenotype. Has little or no effect on the Dsor1XS520 eye phenotype.

        (Karim et al., 1996)
        Xenogenetic Interactions
        Statement
        Reference
        Complementation and Rescue Data
        Comments
        Images (0)
        Mutant
        Wild-type
        Stocks (0)
        Notes on Origin
        Discoverer
        External Crossreferences and Linkouts ( 0 )
        Synonyms and Secondary IDs (1)
        Reported As
        Symbol Synonym
        ER3-3XE-571
        Name Synonyms
        Secondary FlyBase IDs
          References (1)