FB2026_03 , released September 17, 2026
Allele: Ecol\lacZPka-C3.PM
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General Information
Symbol
Ecol\lacZPka-C3.PM
Species
E. coli
Name
cAMP-dependent protein kinase promoter construct of Melendez
FlyBase ID
FBal0049932
Feature type
allele
Associated gene
Ecol\lacZ
Associated Insertion(s)
Carried in Construct
P{DC2-lacZ}
Transgenic product class
Mutagen
Nature of the Allele
Transgenic product class
Mutagen
in vitro construct
(Melendez et al., 1995)
Progenitor genotype
Carried in construct
P{DC2-lacZ}
Cytology
Description

3.5kb of Pka-C3 promoter drives the expression of a lacZ reporter.

(Melendez et al., 1995)
Allele components
Component
Use(s)
Encoded product / tool
lacZ
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      distribution deduced from reporter
      Stage
      Tissue/Position (including subcellular localization)
      Reference
      embryonic stage 9
      head mesoderm
      (Melendez et al., 1995)
      mesoderm
      (Melendez et al., 1995)
      larval stage
      leg disc | restricted
      (Melendez et al., 1995)
      embryonic/larval optic stalk | surrounding
      (Melendez et al., 1995)
      embryonic/larval optic lobe
      (Melendez et al., 1995)
      wing disc | restricted
      (Melendez et al., 1995)
      Additional Information
      Statement
      Reference

      Reporter gene expression is observed in the ventral portion of the embryo as with endogenous Pka-C3 RNA but persists longer and can be seen in the mesoderm of the extending germ band and in the cephalic mesoderm. In larve, expression is observed in the crescent of optic lobe lamina cells surrounding the stalk of the optic nerve, in central regions of the leg discs, and in central regions of the wing disc that develop into the notum.

      (Melendez et al., 1995)
       
      Marker for
      Reflects expression of
      Pka-C3
      (Melendez et al., 1995)
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      Ecol\lacZPka-C3.PM
      lacZPka-C3.PM
      Name Synonyms
      cAMP-dependent protein kinase promoter construct of Melendez
      (Melendez et al., 1995)
      Secondary FlyBase IDs
        References (1)