FB2026_02 , released June 18, 2026
Allele: Dmel\mamU
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General Information
Symbol
Dmel\mamU
Species
D. melanogaster
Name
FlyBase ID
FBal0050128
Feature type
allele
Associated gene
Dmel\mam
Associated Insertion(s)
Carried in Construct
Key Links
Allele class

loss of function allele

Mutagen
    Nature of the Allele
    Allele class

    loss of function allele

    (Williams et al., 1990)
    Mutagen
    Progenitor genotype
    Caused by aberration
    In(2R)vgU
    Cytology
    Description

    Inversion breakpoint within mam at -27 (coordinates are as in FBrf0048222).

    (Williams et al., 1990)
    Mutations Mapped to the Genome
    Curation Data
    Type
    Location
    Additional Notes
    References
    Variant Molecular Consequences
    Associated Sequence Data
    DDBJ / EMBL / GenBank
    DNA sequence
    Protein sequence
     
    UniProtKB/Swiss-Prot
      UniProtKB/TrEMBL
        Expression Data
        Reporter Expression
        Additional Information
        Statement
        Reference
         
        Marker for
        Reflects expression of
        Reporter construct used in assay
        Human Disease Associations
        Disease Ontology (DO) Annotations
        Models Based on Experimental Evidence ( 0 )
        Disease
        Evidence
        References
        Modifiers Based on Experimental Evidence ( 0 )
        Disease
        Interaction
        References
        Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
         
        Disease-implicated variant(s)
         
        Phenotypic Data
        Phenotypic Class
        Phenotype Manifest In
        Detailed Description
        Statement
        Reference

        Homozygous embryos or transheterozygotes with mam8 have a neurogenic phenotype.

        (Williams et al., 1990)
        External Data
        Interactions
        Show genetic interaction network for Enhancers & Suppressors
        Phenotypic Class
        Phenotype Manifest In
        Additional Comments
        Genetic Interactions
        Statement
        Reference
        Xenogenetic Interactions
        Statement
        Reference
        Complementation and Rescue Data
        Comments
        Images (0)
        Mutant
        Wild-type
        Stocks (3)
        Notes on Origin
        Discoverer
        Comments
        Comments

        The homozygous embryonic lethality of In(2R)vgU may just be due to the mamU mutation. It is also possible that homozygous vgU dominance is lethal.

        (Williams et al., 1990)
        External Crossreferences and Linkouts ( 0 )
        Synonyms and Secondary IDs (1)
        Reported As
        Symbol Synonym
        mamU
        Name Synonyms
        Secondary FlyBase IDs
          References (2)