FB2026_03 , released September 17, 2026
Allele: Dmel\trplhs.PN
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General Information
Symbol
Dmel\trplhs.PN
Species
D. melanogaster
Name
heat shock construct of Niemeyer
FlyBase ID
FBal0050671
Feature type
allele
Associated gene
Dmel\trpl
Associated Insertion(s)
Carried in Construct
P{hs-trpl}
Key Links
Transgenic product class
wild_type
(Niemeyer et al., 1996)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Niemeyer et al., 1996)
Mutagen
in vitro construct
(Niemeyer et al., 1996)
Progenitor genotype
Carried in construct
P{hs-trpl}
Cytology
Description

Expression of a 3500bp DNA fragment containing the entire trpl coding region is driven by an Hsp70 promoter.

(Niemeyer et al., 1996)
Allele components
Component
Use(s)
Regulatory region(s)
Hsp70
Encoded product / tool
trpl
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      trplhs.PN rescues trpl302

      (Macpherson et al., 2005)

      trplhs.PN rescues trpl302

      (Niemeyer et al., 1996)
      Comments

      Reintroduction of trplhs.PN to trpl302; trp2 mutants rescues the mutant defect and restores visual physiology. Photoreceptor cells produce quantum bumps (the unitary event of a single photon) that are indistinguishable from wild type.

      (Niemeyer et al., 1996)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      trplhs.PN
      Name Synonyms
      heat shock construct of Niemeyer
      (Niemeyer et al., 1996)
      Secondary FlyBase IDs
        References (2)