FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\shot2
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General Information
Symbol
Dmel\shot2
Species
D. melanogaster
Name
FlyBase ID
FBal0051151
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
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Allele class
Mutagen
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Allele class
Progenitor genotype
Cytology
Description
Mutations Mapped to the Genome
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Associated Sequence Data
DNA sequence
Protein sequence
 
Expression Data
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Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
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Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
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Reference

The lateral chordotonal sensory axons arrest at variable stages before reaching the central nervous system (CNS); 68% extend towards the intersegmental nerve (ISN) and stall or fail to reach the ISN, 32% travel a significant distance within the ISN, but none of the axons reach the CNS border. Defects in LCH dendrite morphology are seen in shot2/shot3 mutant embryos. 6% of ISN axons lack the most dorsal terminal arborisation, 48% lack the 2 most dorsal terminal arborisations and 43% lack all three terminal arborisations in shot2/shot3 embryos. 57% of ISNb motor axons stall in the ventral muscle field (somewhere between muscle 6 and muscle 13) and 30% stall at the muscle field border. 46% of SNa axons have one branch missing (wild-type axons form two branches) and 28% lack both branches.

Mutant phenotype as assayed by Ecol\lacZrp staining: the termini of RP1 and RP3 segmental motor nerve axons missing. Mutant phenotype of lateral chordotonal axons includes: shorter axons.

External Data
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Xenogenetic Interactions
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Complementation and Rescue Data
Fails to complement
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Mutant
Wild-type
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Comments
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (1)
Reported As
Symbol Synonym
shot2
Name Synonyms
Secondary FlyBase IDs
    References (4)