FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\pigeonhs.PB
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General Information
Symbol
Dmel\pigeonhs.PB
Species
D. melanogaster
Name
heat shock construct of Bolwig
FlyBase ID
FBal0051369
Feature type
allele
Associated gene
Dmel\pigeon
Associated Insertion(s)
Carried in Construct
P{hs-pigeon+}
Key Links
Transgenic product class
cDNA
(Bolwig et al., 1995)
wild_type
(Bolwig et al., 1995)
Mutagen
Nature of the Allele
Transgenic product class
cDNA
(Bolwig et al., 1995)
wild_type
(Bolwig et al., 1995)
Mutagen
in vitro construct
(Bolwig et al., 1995)
Progenitor genotype
Carried in construct
P{hs-pigeon+}
Cytology
Description

A 3.1kb pigeon cDNA clone is expressed from an Hsp70 promoter.

(Bolwig et al., 1995)
Allele components
Component
Use(s)
Regulatory region(s)
Hsp70
Encoded product / tool
pigeon
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Fails to rescue

      pigeonhs.PB fails to rescue pigeonP1

      (Bolwig et al., 2002)
      Comments

      Rescue of pigeonP1 adult olfactory learning defect by pigeonhs.PB reported in FBrf0083785 is not reproducible. pigeonhs.PB rescues defects in another form of plasticity.

      (Bolwig et al., 2002)

      Heat shock rescues learning and 3hr retention scores of pigeonP1 to wild-type levels. Perception of odors or electroshock remain normal when heat shock is applied to pigeonP1 flies. Heat shock has no effect on learning and memory in wild-type flies. FlyBase curator comment: In a subsequent publication (Bolwig et al., 2002, Neuron 34: 667) the authors describe how repeat of these rescue experiments failed to reproduce the rescue of the adult learning defect of pigeonP1 by FBtp0006269.

      (Bolwig et al., 1995)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      liohs.PB
      pigeonhs.PB
      Name Synonyms
      heat shock construct of Bolwig
      (Bolwig et al., 1995)
      Secondary FlyBase IDs
        References (2)