FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Scmunspecified
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General Information
Symbol
Dmel\Scmunspecified
Species
D. melanogaster
Name
FlyBase ID
FBal0052109
Feature type
allele
Associated gene
Dmel\Scm
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
    Nature of the Allele
    Allele class
    Mutagen
    Progenitor genotype
    Cytology
    Description

    FlyBase curator comment: this entry is used to capture phenotypic information when the particular allele (or allele combination) used by the author could not be determined but the context of the experiment suggests that the phenotype being described is some kind of loss of function.

    (FlyBase Curators, 2025-)
    Mutations Mapped to the Genome
    Curation Data
    Type
    Location
    Additional Notes
    References
    Variant Molecular Consequences
    Associated Sequence Data
    DDBJ / EMBL / GenBank
    DNA sequence
    Protein sequence
     
    UniProtKB/Swiss-Prot
      UniProtKB/TrEMBL
        Expression Data
        Reporter Expression
        Additional Information
        Statement
        Reference
         
        Marker for
        Reflects expression of
        Reporter construct used in assay
        Human Disease Associations
        Disease Ontology (DO) Annotations
        Models Based on Experimental Evidence ( 0 )
        Disease
        Evidence
        References
        Modifiers Based on Experimental Evidence ( 0 )
        Disease
        Interaction
        References
        Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
         
        Disease-implicated variant(s)
         
        Phenotypic Data
        Phenotypic Class
        Phenotype Manifest In
        Detailed Description
        Statement
        Reference

        Mutants show defects in the axon pattern of class IV dendritic arborization (da) neurons. The axon scaffold shows occasional loss of longitudinal and commissural branches.

        (Grueber et al., 2007)

        Heterozygous and homozygous phenotype is very similar to Pcl mutants.

        (Tearle and Nusslein-Volhard, 1987)

        Abdominal segments in the embryo are transformed posteriorly. In the strongest alleles, the first abdominal segment resembles the second abdominal segment, and abdominal segments 2-7 are transformed to more posterior segments, while the head and thorax are normal. Weaker alleles affect only the more posterior segments. In Pclunspecified Scmunspecified double mutants, all denticle bands are similar to each other, and resemble A8 of wild-type embryos, although the thorax appears less transformed as the Keilin's organs are present. Head involution does not occur. A prominent abdominal denticle appears on the dorsal surface of the head and a few abdominal denticles are found behind the floor of the pharynx.

        (Jurgens, 1985)
        External Data
        Interactions
        Show genetic interaction network for Enhancers & Suppressors
        Phenotypic Class
        Phenotype Manifest In
        Additional Comments
        Genetic Interactions
        Statement
        Reference

        The transformation seen in Scmunspecified heterozygotes is dominantly enhanced by Su(z)121, giving additional sex comb teeth on the second and third legs in male double heterozygous flies.

        (Birve and Rasmuson-Lestander, 1994)
        Xenogenetic Interactions
        Statement
        Reference
        Complementation and Rescue Data
        Comments
        Images (0)
        Mutant
        Wild-type
        Stocks (0)
        Notes on Origin
        Discoverer
        External Crossreferences and Linkouts ( 0 )
        Synonyms and Secondary IDs (2)
        Reported As
        Symbol Synonym
        Scmunspecified
        unspecified
        (Birve and Rasmuson-Lestander, 1994, Jurgens, 1985)
        Name Synonyms
        Secondary FlyBase IDs
          References (6)