FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\NetAUAS.Tag:MYC
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General Information
Symbol
Dmel\NetAUAS.Tag:MYC
Species
D. melanogaster
Name
FlyBase ID
FBal0052149
Feature type
allele
Associated gene
Dmel\NetA
Associated Insertion(s)
Carried in Construct
P{UAS-NetrinA}
Also Known As
UAS-netA
Key Links
Transgenic product class
cDNA
(Mitchell et al., 1996)
wild_type
(Mitchell et al., 1996)
Mutagen
Nature of the Allele
Transgenic product class
cDNA
(Mitchell et al., 1996)
wild_type
(Mitchell et al., 1996)
Mutagen
in vitro construct
(Mitchell et al., 1996)
Progenitor genotype
Carried in construct
P{UAS-NetrinA}
Cytology
Description

UASt regulatory sequences drive expression of a full-length NetA cDNA, tagged at the C-terminal end with the Tag:MYC epitope.

(Mitchell et al., 1996)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
NetA
Tagged with
Tag:MYC
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Scer\GAL4sca-537.4 and Scer\GAL4elav.PLu induced expression in embryos causes commissures that are thinner or nearly absent and bundles of axons that project inappropriately laterally toward the edge of the CNS leaving gaps in the longitudinal tracts. Scer\GAL4how-24B induced expression causes excessive branching of the intersegmental nerve and these branches to stall short of their targets.

      (Mitchell et al., 1996)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments

      Expression of NetAScer\UAS.T:Hsap\MYC under the control of Scer\GAL4sim.PS only weakly rescues the defects in interface glial cell migration seen in Df(1)NetABΔ embryos. The stalling phenotype of the peripheral embryonic glia is not substantially rescued in these animals.

      Expression of NetAScer\UAS.T:Hsap\MYC under the control of Scer\GAL4sca-537.4 completely rescues the defects in interface glial cell migration seen in Df(1)NetABΔ embryos in 90% of embryos.

      (von Hilchen et al., 2010)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      NetAScer\UAS.T:Hsap\MYC
      NetAUAS.T:Myc
      NetAUAS.Tag:MYC
      Name Synonyms
      Secondary FlyBase IDs
        References (5)